ArticleEvidence-based complementary and alternative medicine : eCAM2021
The Effect of Garlic Tablets on the Endometriosis-Related Pains: A Randomized Placebo-Controlled Clinical Trial.
Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Low-FODMAP Diet for Gastrointestinal Symptoms in Endometriosis: A Systematic Review.Nutrients · 2026Pooled it
- Dietary Supplements for Endometriosis-Associated Pain: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.Gynecologic and obstetric investigation · 2026Pooled it
- Efficacy of antioxidant supplementation in alleviating endometriosis-related pain: insights from a systematic review and meta-analysis of RCTs.Reproductive biology and endocrinology : RB&E · 2025Pooled it
- The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Antioxidant vitamins supplementation reduce endometriosis related pelvic pain in humans: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2023Pooled it
- Natural bioactive compounds and herbal medicines targeting common signaling pathways in endometriosis: mechanisms and therapeutic implications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Comparative Effectiveness of Non-Pharmacological Interventions for Pain and Quality of Life in Women with Endometriosis: A Systematic Review and Network Meta-Analysis.Journal of pain research · 2026Review
- Efficacy and safety of traditional Chinese medicine for endometriosis-related pain: a meta-analysis.American journal of translational research · 2025Review
- Therapeutic effects of S-allyl-L-cysteine in a mouse endometriosis model and its immunomodulatory effects via regulation of T cell subsets and cytokine expression.Pharmacological reports : PR · 2024Article
- The impact of vitamin D treatment on pregnancy rate among endometriosis patients: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Holistic approaches to living well with endometriosis.F1000Research · 2024Review
- Aged garlic extract as a potential prophylactic to reduce the progression of endometriosis and associated pain burden.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- The Effects of Chamomile and Flaxseed on Pelvic Pain, Dyspareunia, and Dysmenorrhea in Endometriosis: A Controlled Randomized Clinical Trial.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a common chronic inflammatory disease. Garlic contains components that have antiproliferative, anti-inflammatory, and antioxidative effects. The current study aimed to evaluate the effectiveness of garlic on endometriosis symptoms. This was a randomized placebo-controlled triple-blind clinical trial. A convenience sample of 60 women was randomly allocated into two groups. The intervention group received usual care supplemented with 400 mg garlic tablets, and the placebo group received identical placebo tablets. A four-part Visual Analogue Scale (VAS) was used to measure the severity of pains. The pains were measured on four occasions (before the intervention and on one-, two-, and three-month follow-ups). Data were analyzed using the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.