Evidence map›Paper›PMID 34335815›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Huotan Jiedu Tongluo Decoction Inhibits Balloon-Injury-Induced Carotid Artery Intimal Hyperplasia in the Rat through the PERK-eIF2

Tenghui Tian, Keying Yu, Miao Zhang, Xiao Shao, Liping Chang, Rui Shi, Baojin Yao, Yue Deng

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tenghui TianChangchun University of Chinese Medicine, Changchun 130117, Jilin, China.ORCID https://orcid.org/0000-0001-5578-0962
Keying YuHospital of Affiliated Changchun University of Chinese Medicine, Changchun 130021, Jilin, China.ORCID https://orcid.org/0000-0002-0438-5273
Miao ZhangChangchun University of Chinese Medicine, Changchun 130117, Jilin, China.ORCID https://orcid.org/0000-0002-1131-9864
Xiao ShaoChangchun University of Chinese Medicine, Changchun 130117, Jilin, China.ORCID https://orcid.org/0000-0002-2237-3823
Liping ChangHospital of Affiliated Changchun University of Chinese Medicine, Changchun 130021, Jilin, China.ORCID https://orcid.org/0000-0002-4350-1214
Rui ShiHospital of Affiliated Changchun University of Chinese Medicine, Changchun 130021, Jilin, China.ORCID https://orcid.org/0000-0002-2174-6819
Baojin YaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China.ORCID https://orcid.org/0000-0002-7542-1585
Yue DengHospital of Affiliated Changchun University of Chinese Medicine, Changchun 130021, Jilin, China.ORCID https://orcid.org/0000-0003-3522-6088
Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In-stent restenosis (ISR) is the main factor affecting the outcome of percutaneous coronary intervention (PCI), and its main pathological feature is neointimal hyperplasia. Huotan Jiedu Tongluo decoction (HTJDTLD) is an effective traditional Chinese medicine (TCM) prescription for the treatment of vascular stenosis diseases. However, the precise anti-ISR mechanism of HTJDTLD remains unclear. Here, we investigated whether HTJDTLD can inhibit the excessive activation of endoplasmic reticulum stress (ERS) and reduce the level of autophagy factors through regulating the PERK-eIF2

Identifiers

PMID34335815
PMCPMC8318774
OpenAlexW3186371213

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.