ReviewInternational journal of dentistry2021
Diagnostic Accuracy of CBCT for Detection of Second Canal of Permanent Teeth: A Systematic Review and Meta-Analysis.
Review in International journal of dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Artificial Intelligence for Working Length Determination in Endodontics: A Systematic Review and Meta-Analysis.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Pooled it
- Mapping risk of bias criteria in systematic reviews of in vitro endodontic studies: an umbrella review.Evidence-based dentistry · 2025Pooled it
- Use of artificial intelligence for detection of MB2 canals in maxillary first molars on CBCT: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Endodontic Management of a Mandibular Central Incisor With Vertucci Type V Configuration: A Case Report From Nepal.Clinical case reports · 2026Article
- Clinical Readiness of Artificial Intelligence Models for MB2 Canal Detection in Maxillary Molars: A Scoping Review.International dental journal · 2026Article
- Cone-beam computed tomographic analysis of dentinal wall thickness in the danger zone of the first and second mesiobuccal canals of maxillary first molars.Journal of conservative dentistry and endodontics · 2026Article
- Single-Visit Endodontics Under Dental Operating Microscopy: A Retrospective Observational Study.Cureus · 2026Article
- Deep learning-based detection of the second mesiobuccal canal in maxillary first molars using cone-beam computed tomography.BMC oral health · 2026Article
- Influence of endodontic access cavity design on root canal localization in mandibular first premolars using microscope and ultrasonic tips.Scientific reports · 2026Article
- Application of machine learning in predicting of MB2 canal in permanent maxillary first and second molars: A CBCT study.PloS one · 2026Article
- Navigating Trifurcated Root Anatomy in Maxillary Premolars: A Detailed Endodontic Case Series.Case reports in dentistry · 2026Article
- High-resolution CBCT Evaluation of Second Mesiobuccal Canal Configuration According to Vertucci's Classification in Maxillary First Molars: An Iranian Population Study.Iranian endodontic journal · 2026Article
- Three-dimensional evaluation of root canal morphology in mandibular premolars of Saudi individuals: a CBCT study.The Libyan journal of medicine · 2025Article
- Literature review and case study: unveiling the complexities of mandibular second molar with three distal canals.BMC oral health · 2024Review
- The Correlation between Intraorifice Distance and the Anatomical Characteristics of the Second Mesiobuccal Canal of Maxillary Molars: A CBCT Study.International journal of dentistry · 2024Article
- Human Bone Typing Using Quantitative Cone-Beam Computed Tomography.International dental journal · 2023Article
- Variables That Affect the Ability to Find the Second Mesiobuccal Root Canals in Maxillary Molars.Iranian endodontic journal · 2023Article
- Artificial Intelligence (AI) for Detection and Localization of Unobturated Second Mesial Buccal (MB2) Canals in Cone-Beam Computed Tomography (CBCT).Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMissed canal is one of the common reasons for nonsurgical endodontic retreatments. The missed canals were frequently associated with periapical pathology. The aim of this systematic review was to find the diagnostic accuracy of CBCT for detection of the second canal of the root canal system of permanent teeth. MATERIALS AND
methodsThe articles were selected from seven electronic databases according to selection criteria. All eligible studies were judged by the reviewers. The selected studies were checked with the QUADAS-2 tool for risk of bias and applicability concerns. Finally, 12 studies were selected for qualitative and quantitative analyses. The summary estimates of sensitivities and specificities and SROC curves were calculated and drawn by RevMan 5.3 and MetaDTA software.
resultsSummary estimates of CBCT for detection of second canal anatomy in permanent teeth were 94% sensitivity and 93.1% specificity. 96.6% sensitivity of MB2 was followed by 88.8% sensitivity of maxillary and mandibular premolars and 81% that of mandibular molars. The specificity of 97.6% for premolars was trialed by 85% specificity of mandibular molars and MB2. For permanent mandibular canines, 67% sensitivity and 100% specificity were estimated. CBCT showed more agreement with detecting the second canal with micro-CT, estimating 100% sensitivity and 95.6% specificity. The highest prevalence of the second canal comprised the highest sensitivity of 99.1% and lowest specificity of 77.5%. After the exclusion of case-control studies, a 3% drop of sensitivity from the summary estimate was observed. Multiple spectrum of the second canal had 8.6% higher sensitivity and 4.4% lower specificity than single spectrum.
conclusionCBCT is informative for detecting the second canal. Clinicians should keep in mind that the accuracy can vary in different types of teeth, with the prevalence of second canal across different populations, and with the spectrum of second canal anatomy in spite of the reviewers having postulated overestimation of the findings.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.