Evidence map›Paper›PMID 34335681›Full record

ArticleFrontiers in genetics2021

Association of Protective

Jessika Nordin, Mats Pettersson, Lina Hultin Rosenberg, Argyri Mathioudaki, Åsa Karlsson, Eva Murén, Karolina Tandre, Lars Rönnblom, Alf Kastbom, Jan Cedergren and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jessika NordinScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Mats PetterssonScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Lina Hultin RosenbergScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Argyri MathioudakiScience for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Åsa KarlssonScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Eva MurénScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Karolina TandreScience for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Lars RönnblomScience for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Alf KastbomDepartment of Rheumatology, University Hospital Linköping, Linköping, Sweden.
Jan CedergrenDepartment of Rheumatology, University Hospital Linköping, Linköping, Sweden.
Per ErikssonDepartment of Rheumatology, University Hospital Linköping, Linköping, Sweden.
Peter SöderkvistDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Kerstin Lindblad-TohScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Jennifer R S MeadowsScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Uppsala University · SELinköping University · SEScience for Life Laboratory · SEBroad Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo further elucidate the role of the MHC in ankylosing spondylitis by typing 17 genes, searching for

methodsHigh-confidence two-field resolution genotyping was performed on 310 cases and 2196 controls using an

resultsTwenty-five

conclusionPopulation stratification allowed for a nuanced investigation into the tightly linked MHC region, revealing novel

Indexed as

ankylosing spondylitisHLA-A∗24:02HLA allele typingHLA-B∗27 positivemajor histocompatibility complexsex biased

Identifiers

PMID34335681
PMCPMC8320510
OpenAlexW3184826059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.