Evidence map›Paper›PMID 34335667›Full record

ArticleFrontiers in plant science2021

Production of Human Acid-Alpha Glucosidase With a Paucimannose Structure by Glycoengineered

Ratna Sariyatun, Florence, Hiroyuki Kajiura, Takao Ohashi, Ryo Misaki, Kazuhito Fujiyama

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Engineering the mossFrontiers in plant science · 2025
    Article
  4. Review
  5. Production andFrontiers in plant science · 2023
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ratna SariyatunLaboratory of Applied Microbiology, International Center for Biotechnology, Osaka University, Suita, Japan.
FlorenceLaboratory of Applied Microbiology, International Center for Biotechnology, Osaka University, Suita, Japan.
Hiroyuki KajiuraLaboratory of Applied Microbiology, International Center for Biotechnology, Osaka University, Suita, Japan.
Takao OhashiLaboratory of Applied Microbiology, International Center for Biotechnology, Osaka University, Suita, Japan.
Ryo MisakiLaboratory of Applied Microbiology, International Center for Biotechnology, Osaka University, Suita, Japan.
Kazuhito FujiyamaLaboratory of Applied Microbiology, International Center for Biotechnology, Osaka University, Suita, Japan.
Osaka University · JPMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant cell cultures have emerged as a promising platform for the production of biopharmaceutics due to their cost-effectiveness, safety, ability to control the cultivation, and secrete products into culture medium. However, the use of this platform is hindered by the generation of plant-specific

Indexed as

acid-alpha glucosidasealg3GAApaucimannosePompe diseaseα1,3 mannosyltransferase

Identifiers

PMID34335667
PMCPMC8318038
OpenAlexW3182903829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.