Evidence map›Paper›PMID 34335618›Full record

ArticleFrontiers in immunology2021

Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8

Corinne J Smith, Christopher M Snyder

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Purinergic Signaling in Ovarian Carcinoma.Advanced pharmaceutical bulletin · 2025
    Review
  3. Article
  4. NK cells restrain cytotoxic CD8Science immunology · 2024
    Article
  5. Alarm Functions of PD-1+ Brain-Resident Memory T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Article
  6. Article
  7. Review
  8. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  9. Review
  10. TGF-β Regulation of T Cells.Annual review of immunology · 2023
    Review
  11. IL-10-Secreting CD8Pathogens (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Corinne J SmithDepartment of Microbiology and Immunology, Sidney Kimmel Medical College, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States.
Christopher M SnyderDepartment of Microbiology and Immunology, Sidney Kimmel Medical College, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States.
Sidney Kimmel Cancer Center · USThomas Jefferson University · US

Funding

T cell control of MCMV and tissue-localized immune suppressionR01AI146235 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI SNYDER, CHRISTOPHER M · 2020 to 2024
$2.7M
Selection of inflationary and tissue-resident T cells during MCMV infectionR01AI106810 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI SNYDER, CHRISTOPHER M · 2014 to 2018
$1.7M
Selection of inflationary and tissue-resident T cells during MCMV infectionR56AI106810 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI SNYDER, CHRISTOPHER M · 2013 to 2013
$364k
NIAID NIH HHS R01 AI106810NIAID NIH HHS R01 AI146235NIAID NIH HHS R56 AI106810
6 · The paper itself

Abstract

The salivary gland is an important tissue for persistence and transmission of multiple viruses. Previous work showed that salivary gland tissue-resident CD8

Indexed as

5'-NucleotidaseAnimalsAntigens, CDApyraseCD8-Positive T-LymphocytesGene Expression RegulationMiceMice, KnockoutOrgan SpecificityProgrammed Cell Death 1 ReceptorTime Factors5'-NucleotidaseAntigens, CDApyraseCD39 antigenPdcd1 protein, mouseProgrammed Cell Death 1 ReceptorCD73CD8 T cellscytomegalovirus (CMV)PD-1tissue-resident CD8+ T cell

Identifiers

PMID34335618
PMCPMC8320728
OpenAlexW3186689255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.