Evidence map›Paper›PMID 34335541›Full record

ArticleFrontiers in microbiology2021

Increased Virulence of Outer Membrane Porin Mutants of

Vinicius C N de Moura, Deepshikha Verma, Isobel Everall, Karen P Brown, Juan M Belardinelli, Crystal Shanley, Megan Stapleton, Julian Parkhill, R Andres Floto, Diane J Ordway and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Mechanisms of Antimicrobial Resistance inInfection and drug resistance · 2025
    Review
  7. Evolution toward extremely high imipenem resistance inAntimicrobial agents and chemotherapy · 2024
    Article
  8. Evolution towards extremely high β-lactam resistance inbioRxiv : the preprint server for biology · 2024
    Article
  9. Evolution ofVirulence · 2023
    Article
  10. Virulence Mechanisms ofFrontiers in microbiology · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Vinicius C N de MouraMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Deepshikha VermaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Isobel EverallMolecular Immunity Unit, Medical Research Council (MRC)-Laboratory of Molecular Biology, University of Cambridge Department of Medicine, Cambridge, United Kingdom.
Karen P BrownMolecular Immunity Unit, Medical Research Council (MRC)-Laboratory of Molecular Biology, University of Cambridge Department of Medicine, Cambridge, United Kingdom.
Juan M BelardinelliMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Crystal ShanleyMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Megan StapletonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Julian ParkhillDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
R Andres FlotoMolecular Immunity Unit, Medical Research Council (MRC)-Laboratory of Molecular Biology, University of Cambridge Department of Medicine, Cambridge, United Kingdom.
Diane J OrdwayMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Mary JacksonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, United States.
Colorado State University · USUniversity of Cambridge · GBMedical Research Council · GBWellcome Sanger Institute · GB

Funding

Disinfectant-resistant mycobacteriaR01AI089718 · NIAID · COLORADO STATE UNIVERSITY · PI JACKSON, MARY · 2011 to 2015
$1.8M
NIAID NIH HHS R01 AI089718
6 · The paper itself

Abstract

Chronic pulmonary infections caused by non-tuberculous mycobacteria of the

Indexed as

abscessusantibiotic resistanceMycobacteriumporinvirulence

Identifiers

PMID34335541
PMCPMC8317493
OpenAlexW3181853659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.