Evidence map›Paper›PMID 34335457›Full record

ArticleFrontiers in neurology2021

Forecasting Seizure Likelihood With Wearable Technology.

Rachel E Stirling, David B Grayden, Wendyl D'Souza, Mark J Cook, Ewan Nurse, Dean R Freestone, Daniel E Payne, Benjamin H Brinkmann, Tal Pal Attia, Pedro F Viana and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Wearable Artificial Intelligence for Epilepsy: Scoping Review.Journal of medical Internet research · 2025
    Article
  12. Rhythms in Longitudinal Thalamic Recordings are Linked to Seizure Risk.medRxiv : the preprint server for health sciences · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Rachel E StirlingDepartment of Biomedical Engineering, The University of Melbourne, Melbourne, VIC, Australia.
David B GraydenDepartment of Biomedical Engineering, The University of Melbourne, Melbourne, VIC, Australia.
Wendyl D'SouzaDepartments of Medicine and Neurology, St Vincent's Hospital, The University of Melbourne, Melbourne, VIC, Australia.
Mark J CookDepartments of Medicine and Neurology, St Vincent's Hospital, The University of Melbourne, Melbourne, VIC, Australia.
Ewan NurseDepartments of Medicine and Neurology, St Vincent's Hospital, The University of Melbourne, Melbourne, VIC, Australia.
Dean R FreestoneSeer Medical, Melbourne, VIC, Australia.
Daniel E PayneDepartment of Biomedical Engineering, The University of Melbourne, Melbourne, VIC, Australia.
Benjamin H BrinkmannBioelectronics Neurophysiology and Engineering Lab, Department of Neurology, Mayo Clinic, Rochester, MN, United States.
Tal Pal AttiaBioelectronics Neurophysiology and Engineering Lab, Department of Neurology, Mayo Clinic, Rochester, MN, United States.
Pedro F VianaSchool of Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Mark P RichardsonSchool of Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Philippa J KarolyDepartment of Biomedical Engineering, The University of Melbourne, Melbourne, VIC, Australia.
St Vincent's Hospital · AUUniversity of Melbourne · AUBioElectronics (United States) · USKing's College London · GBMayo Clinic · USUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unpredictability of epileptic seizures exposes people with epilepsy to potential physical harm, restricts day-to-day activities, and impacts mental well-being. Accurate seizure forecasters would reduce the uncertainty associated with seizures but need to be feasible and accessible in the long-term. Wearable devices are perfect candidates to develop non-invasive, accessible forecasts but are yet to be investigated in long-term studies. We hypothesized that machine learning models could utilize heart rate as a biomarker for well-established cycles of seizures and epileptic activity, in addition to other wearable signals, to forecast high and low risk seizure periods. This feasibility study tracked participants' (

Indexed as

circadian rhythmscycles (cyclical)multiday rhythmsseizure cyclesseizure forecastingwearable sensors

Identifiers

PMID34335457
PMCPMC8320020
OpenAlexW3165325799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.