Evidence map›Paper›PMID 34335454›Full record

ArticleFrontiers in neurology2021

Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the

Milvia Alata, Arturo González-Vega, Valeria Piazza, Anke Kleinert-Altamirano, Carmen Cortes, Juan C Ahumada-Juárez, Jose R Eguibar, Alejandra López-Juárez, Victor H Hernandez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Milvia AlataCenter of Research in Optics, Leon, Mexico.
Arturo González-VegaDepartment of Chemical, Electronic and Biomedical Engineering, Division of Sciences and Engineering, University of Guanajuato, Guanajuato, Mexico.
Valeria PiazzaCenter of Research in Optics, Leon, Mexico.
Anke Kleinert-AltamiranoCenter of Rehabilitation and Child Inclusion Teleton, Chiapas, Mexico.
Carmen CortesBehavioral Neurophysiology Lab, Institute of Physiology, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Juan C Ahumada-JuárezBehavioral Neurophysiology Lab, Institute of Physiology, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Jose R EguibarBehavioral Neurophysiology Lab, Institute of Physiology, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Alejandra López-JuárezDepartment of Chemical, Electronic and Biomedical Engineering, Division of Sciences and Engineering, University of Guanajuato, Guanajuato, Mexico.
Victor H HernandezDepartment of Chemical, Electronic and Biomedical Engineering, Division of Sciences and Engineering, University of Guanajuato, Guanajuato, Mexico.
Benemérita Universidad Autónoma de Puebla · MXUniversidad de Guanajuato · MXCentro de Investigaciones en Optica · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) is a central neurodegenerative disease due to mutations in the tubulin beta-4A (TUBB4A) gene, characterized by motor development delay, abnormal movements, ataxia, spasticity, dysarthria, and cognitive deficits. Diagnosis is made by integrating clinical data and radiological signs. Differences in MRIs have been reported in patients that carry the same mutation; however, a quantitative study has not been performed so far. Our study aimed to provide a longitudinal analysis of the changes in the cerebellum (Cb), corpus callosum (CC), ventricular system, and striatum in a patient suffering from H-ABC and in the

Indexed as

ataxiacerebellumdemyelinationH-ABCmyelinquantitative MRIsegmentation (image processing)tubulinopathy

Identifiers

PMID34335454
PMCPMC8317997
OpenAlexW3184682247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.