Evidence map›Paper›PMID 34335304›Full record

ArticleFrontiers in physiology2021

Amadis: A Comprehensive Database for Association Between Microbiota and Disease.

Long Li, Qingxu Jing, Sen Yan, Xuxu Liu, Yuanyuan Sun, Defu Zhu, Dawei Wang, Chenjun Hao, Dongbo Xue

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Microbial cell (Graz, Austria) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Long LiDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Qingxu JingDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Sen YanDepartment of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xuxu LiuDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yuanyuan SunDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Defu ZhuFamily Medicine General Practice Clinic, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Dawei WangDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Chenjun HaoDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Dongbo XueDepartment of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
First Affiliated Hospital of Harbin Medical University · CNHarbin Medical University · CNUniversity of Hong Kong - Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gastrointestinal tract represents a symbiotic bioreactor that can mediate the interaction of the human host. The deployment and integration of multi-omics technologies have depicted a more complete image of the functions performed by microbial organisms. In addition, a large amount of data has been generated in a short time. However, researchers struggling to keep track of these mountains of information need a way to conveniently gain a comprehensive understanding of the relationship between microbiota and human diseases. To tackle this issue, we developed Amadis (http://gift2disease.net/GIFTED), a manually curated database that provides experimentally supported microbiota-disease associations and a dynamic network construction method. The current version of the Amadis database documents 20167 associations between 221 human diseases and 774 gut microbes across 17 species, curated from more than 1000 articles. By using the curated data, users can freely select and combine modules to obtain a specific microbe-based human disease network. Additionally, Amadis provides a user-friendly interface for browsing, searching and downloading. We hope it can serve as a useful and valuable resource for researchers exploring the associations between gastrointestinal microbiota and human diseases.

Indexed as

bioinformaticsdatabasegut microbiotahuman diseasesnetwork

Identifiers

PMID34335304
PMCPMC8317061
OpenAlexW3179076314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.