Evidence map›Paper›PMID 34335228›Full record

ArticleFrontiers in aging neuroscience2021

Futoshi Eto, Takeshi Yoshimoto, Shuhei Okazaki, Kunihiro Nishimura, Shiori Ogura, Eriko Yamaguchi, Kazuki Fukuma, Satoshi Saito, Kazuo Washida, Masatoshi Koga and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Genes · 2025
    Review
  5. Journal of the American Heart Association · 2025
    Article
  6. Relationship BetweenJournal of the American Heart Association · 2025
    Article
  7. Review
  8. Association of theStroke (Hoboken, N.J.) · 2022
    Article
  9. Impact of theStroke (Hoboken, N.J.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Futoshi EtoDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Takeshi YoshimotoDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Shuhei OkazakiDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Kunihiro NishimuraDepartment of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center, Suita, Japan.
Shiori OguraDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Eriko YamaguchiDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Kazuki FukumaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Satoshi SaitoDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Kazuo WashidaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
Masatoshi KogaDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Kazunori ToyodaDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Takaaki MorimotoDepartment of Neurosurgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan.
Hirofumi MaruyamaDepartment of Clinical Neuroscience and Therapeutics, Hiroshima University, Hiroshima, Japan.
Akio KoizumiDepartment of Health and Environmental Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masafumi IharaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.
National Cerebral and Cardiovascular Center · JPHiroshima University · JPHyogo Prefectural Amagasaki General Medical Center · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDysregulation of the RING finger protein 213 PATIENTS AND

methodsThe present study is an observational cross-sectional study. It included patients with acute anterior circulation non-cardioembolic stroke admitted to our institution within 7 days of symptom onset or last-known-well from 2011 to 2019, and those who participated in the National Cerebral and Cardiovascular Center Biobank. We compared anatomical variations of the vessels constituting the circle of Willis between

resultsFour hundred eighty-one patients [146 women (30%); median age 70 years; median baseline National Institutes of Health Stroke Scale score 5] were analyzed. The

conclusionOur findings suggest that the

Indexed as

cerebral circulationmagnetic resonance angiographyRNF213 p.R4810Ksingle nucleotide polymorphismthe circle of Willis

Identifiers

PMID34335228
PMCPMC8322682
OpenAlexW3179943121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.