Evidence map›Paper›PMID 34335061›Full record

ArticleRisk management and healthcare policy2021

Estimating the Transmission Risks of Viral Hepatitis and HIV Among Blood Donors in Hossana, Southern Ethiopia.

Gizachew Beykaso, Tilahun Teklehaymanot, Mirutse Giday, Nega Berhe, Feleke Doyore, Dawit Hailu Alemayehu, Adane Mihret, Andargachew Mulu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Risk management and healthcare policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gizachew BeykasoAklilu Lemma Institute of Pathobiology, Department of Molecular Biology and Genetics, Addis Ababa University, Addis Ababa, Ethiopia.
Tilahun TeklehaymanotAklilu Lemma Institute of Pathobiology, Department of Molecular Biology and Genetics, Addis Ababa University, Addis Ababa, Ethiopia.
Mirutse GidayAklilu Lemma Institute of Pathobiology, Department of Molecular Biology and Genetics, Addis Ababa University, Addis Ababa, Ethiopia.
Nega BerheAklilu Lemma Institute of Pathobiology, Department of Molecular Biology and Genetics, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0001-6959-989X
Feleke DoyoreCollege of Medicine and Health Sciences, Department of Public Health, Wachemo University, Hossana, Ethiopia.ORCID 0000-0002-9311-9275
Dawit Hailu AlemayehuArmauer Hansen Research Institute, Department of Virology, Addis Ababa, Ethiopia.
Adane MihretArmauer Hansen Research Institute, Department of Virology, Addis Ababa, Ethiopia.
Andargachew MuluArmauer Hansen Research Institute, Department of Virology, Addis Ababa, Ethiopia.
Addis Ababa University · ETArmauer Hansen Research Institute · ETWachemo University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeScreening of viral transfusion-transmissible infections (TTIs) among blood donors is of public health concern. It is a cost-effective method to monitor the occurrence, distribution, and trends of TTIs in healthy people. This study aimed to estimate the magnitude of the three common viral TTIs among blood donors in Hossana, Ethiopia.

methodsA cross-sectional study was conducted among 417 blood donors from April to May 2020 in Southern Ethiopia. Data were collected using a structured questionnaire and laboratory blood screening for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) using Wantai AiDTM HBsAg, anti-HCV, and HIV 1 + 2 Ag/Ab ELISA. Data were entered into Epi-Data version 3.1 and analyzed using SPSS version 21.0. A binary logistic regression model was fitted to identify factors associated with each viral infection. The odds ratio with a 95% confidence interval was calculated. A p-value <0.05 was considered statistically significant.

resultsA total of 417 blood donors participated in this study producing an overall prevalence of viral TTI was 14.38%. HBV, HCV, and HIV prevalence were 9.83%, 2.39%, and 4.31%, respectively. HBV-HIV was a common co-infection, which had 1.2%. In multivariate logistic regression analysis, family history of hepatitis (AOR=5.2, 95% CI (2.92, 7.41)) and multiple sexual contacts (AOR=4.2, 95% CI (2.32-7.43)) were significantly associated with HBV; low educational level (AOR=3.1, 95% CI (2.58-15.25)) and multiple sexual contacts (AOR=4.9, 95% CI (3.51-7.96)) were significantly associated with HIV, but the only variable alcohol consumption (AOR=2.7, 95% CI (6.72-23.76)) was also associated with HCV infection.

conclusionIn this study, the magnitude of viral TTIs among blood donors is high. This indicates that there are high risks of transmission for these infectious pathogens. Therefore, effective stringent donor selection and screening protocols should be developed.

Indexed as

blood transfusionHBVHCVHIVseroprevalence

Identifiers

PMID34335061
PMCPMC8318006
OpenAlexW3184679109

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.