Evidence map›Paper›PMID 34334965›Full record

ArticleExpert systems with applications2021

A deep-learning-based framework for severity assessment of COVID-19 with CT images.

Zhidan Li, Shixuan Zhao, Yang Chen, Fuya Luo, Zhiqing Kang, Shengping Cai, Wei Zhao, Jun Liu, Di Zhao, Yongjie Li

Abstract read
In one paragraph

Article in Expert systems with applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Construction of a predictive model for radiation proctitis after radiotherapy for female pelvic tumors based on machine learning.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  17. Article
  18. Detection and Prevention of Virus Infection.Advances in experimental medicine and biology · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhidan LiMOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Shixuan ZhaoMOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Yang ChenWest China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, China.
Fuya LuoMOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Zhiqing KangMOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Shengping CaiDepartment of Radiology, Wuhan Red Cross Hospital, Wuhan, China.
Wei ZhaoDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Jun LiuDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Di ZhaoInstitute of Computing Technology, Chinese Academy of Sciences, Beijing, China.
Yongjie LiMOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Millions of positive COVID-19 patients are suffering from the pandemic around the world, a critical step in the management and treatment is severity assessment, which is quite challenging with the limited medical resources. Currently, several artificial intelligence systems have been developed for the severity assessment. However, imprecise severity assessment and insufficient data are still obstacles. To address these issues, we proposed a novel deep-learning-based framework for the fine-grained severity assessment using 3D CT scans, by jointly performing lung segmentation and lesion segmentation. The main innovations in the proposed framework include: 1) decomposing 3D CT scan into multi-view slices for reducing the complexity of 3D model, 2) integrating prior knowledge (dual-Siamese channels and clinical metadata) into our model for improving the model performance. We evaluated the proposed method on 1301 CT scans of 449 COVID-19 cases collected by us, our method achieved an accuracy of 86.7% for four-way classification, with the sensitivities of 92%, 78%, 95%, 89% for four stages. Moreover, ablation study demonstrated the effectiveness of the major components in our model. This indicates that our method may contribute a potential solution to severity assessment of COVID-19 patients using CT images and clinical metadata.

Indexed as

Clinical metadataCOVID-19Deep learningDual-Siamese channelsMulti-view lesionSeverity assessment

Identifiers

PMID34334965
PMCPMC8314790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.