ArticleJournal of addiction medicine
Preconception Substance Use and Risk of Unintended Pregnancy: Pregnancy Risk Assessment Monitoring System 2016-17.
Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Effect of E-learning clinical management of substance-dependent pregnant women on the knowledge and clinical skill performance of midwives: a randomized controlled trial.BMC pregnancy and childbirth · 2025Trial
- Contraception use among individuals with substance use disorder increases tenfold with patient-centered, mobile services: a quasi-experimental study.Harm reduction journal · 2023Trial
- "My story is good… It's not like that for all": Uneven access to contraception among incarcerated women in New South Wales, Australia.Reproductive health · 2026Article
- Perspectives of professionals on the perinatal period as a window of opportunity for change in women with SUD: insights from healthcare, child welfare, substance use, and child protection services.Frontiers in psychiatry · 2026Article
- Alcohol and drug use and attainment of pregnancy preferences in the southwestern United States: A longitudinal cohort study.Addiction (Abingdon, England) · 2025Article
- An exploratory study on the use of sexually transmitted infection prevention and contraception methods among women and men who use unprescribed opioids.Drug and alcohol dependence reports · 2025Article
- Planning postpartum contraception for women with substance use disorders: Utilisation of the birth admission.The Australian & New Zealand journal of obstetrics & gynaecology · 2025Article
- Pregnancy intention, preconception health, health behaviours, and information and health advice seeking among expectant male partners.BMC primary care · 2025Article
- Exploring the harm reduction paradigm: the role of Board-Certified Psychiatric Pharmacists.The mental health clinician · 2024Article
- Factors associated with unintended pregnancy and contraceptive practices in justice-involved adolescent girls in Australia.PloS one · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThis study examined the association between preconception substance use and unintended pregnancy in a large, nationally representative sample of women.
methodsIn this cross-sectional study, we used data from the Pregnancy Risk Assessment Monitoring System (PRAMS) comprising, 74,543women who had birth during 2016-17. Logistic regression was used to assess the independent association of unintended pregnancy overall and by subtypes to preconception substance use (smoking and other nicotine/tobacco use, alcohol consumption, and use of cannabis, illicit/recreational drugs) and specific medication including prescription opioids, antidepressants and over the counter pain relief.
resultsOverall, 41% of pregnancies were unintended. Nearly 57% of participants reported alcohol consumption during the preconception period, with 32% indicating binge drinking, 17% reported preconception smoking, and 10% cannabis use. Unintended pregnancy was significantly associated with substance use, including smoking (adjusted odds ratio [AOR]:1.5, 95% confidence interval [CI]: 1.4-1.6); as well as the use of other nicotine/tobacco (AOR:1.4, 95% CI: 1.3-1.5); cannabis (AOR: 1.9, 95% CI: 1.5-2.3); illicit/recreational drugs (AOR:1.7, 95% CI: 1.2-2.4), prescription opioids (AOR:1.4, 95% CI: 1.02-1.9), and prescription antidepressants (AOR 1.8, 95% CI: 1.1-3.0). The likelihood of unintended pregnancy was significantly elevated with heavy smoking, heavy alcohol consumption, and binge drinking. Analyses by unintended pregnancy subtype yielded similar results.
conclusionsPreconception substance use was significantly and positively associated with unintended pregnancy. Evidence-based interventions are needed addressing substance use behavior and effective contraceptive use to prevent unintended pregnancy and related adverse effects on maternal and child health.
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Registered trials
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