Evidence map›Paper›PMID 34334531›Full record

ArticleJournal of clinical and experimental hematopathology : JCEH2021

Establishment of an ATLL cell line (YG-PLL) dependent on IL-2 and IL-4, which are replaced by OX40-ligand

Yoshitoyo Kagami, Harumi Kato, Yasutaka Okada, Masao Seto, Kazuhito Yamamoto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental hematopathology : JCEH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yoshitoyo KagamiDepartment of Hematology, Toyota Kosei Hospital, Toyota, Aichi, Japan.
Harumi KatoDepartment of Hematology and Cell Therapy, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Yasutaka OkadaDepartment of Clinical Laboratories, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Masao SetoDivision of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.
Kazuhito YamamotoDepartment of Hematology and Cell Therapy, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Aichi Cancer Center · JPAichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We established an IL-2 and IL-4 (IL2/4) - dependent adult T-cell leukemia/lymphoma (ATLL) cell line (YG-PLL) by adding poly-L-lysine (PLL) to the culture medium. YG-PLL originates from lymphoma cells and contains a defective HTLV-I proviral genome. Although YG-PLL cannot survive without IL-2/4, the follicular dendritic cell (FDC)-like cell line HK expressing OX40-ligand gene (OX40L

Indexed as

Cell Line, TumorDendritic Cells, FollicularDermatan SulfateGene ExpressionHistidineHumansInterleukin-2Interleukin-4Leukemia-Lymphoma, Adult T-CellOX40 LigandDermatan SulfateHistidineInterleukin-2Interleukin-4OX40 LigandpolyhistidineTNFSF4 protein, humanAdult T-cell leukemia/lymphomaFollicular dendritic cellInterleukinOX-40 ligandSoluble high-molecular-weight polymer

Identifiers

PMID34334531
PMCPMC8519244
OpenAlexW3188783741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.