Evidence map›Paper›PMID 34334353›Full record

ArticleJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi2022

A hospital cluster of COVID-19 associated with a SARS-CoV-2 superspreading event.

Po-Yen Huang, Ting-Shu Wu, Chun-Wen Cheng, Chih-Jung Chen, Chung-Guei Huang, Kuo-Chien Tsao, Chun-Sui Lin, Ting-Ying Chung, Chi-Chun Lai, Cheng-Ta Yang and 3 more

Abstract read
In one paragraph

Article in Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Risk assessment of infection of COVID-19 contacts based on scenario simulation.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. How Taiwan has responded to COVID-19 and how COVID-19 has affected Taiwan, 2020-2022.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2023
    Review
  8. Article
  9. Control of an outbreak of COVID-19 at a tertiary hospital in Taiwan.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2022
    Article
  10. Characteristics, contacts, and relative risk of SARS-CoV-2 infection among children during school closures.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2022
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Po-Yen HuangDivision of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Infection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Ting-Shu WuDivision of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Infection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chun-Wen ChengDivision of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Infection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chih-Jung ChenInfection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chung-Guei HuangDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan; Research Center for Emerging Viral Infections, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Kuo-Chien TsaoDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan; Research Center for Emerging Viral Infections, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chun-Sui LinInfection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Ting-Ying ChungInfection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chi-Chun LaiInfection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Cheng-Ta YangDepartment of Thoracic Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Yi-Ching ChenDivision of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Cheng-Hsun ChiuInfection Control Committee, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan; Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan. Electronic address: chchiu@adm.cgmh.org.tw.
Infection Control Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeSuperspreading events (SSEs) are pivotal in the spread of SARS-CoV-2. This study aimed to investigate an SSE of COVID-19 in a hospital and explore the transmission dynamics and heterogeneity of SSE.

methodsWe performed contact tracing for all close contacts in a cluster. We did nasopharyngeal or throat swabbing for SARS-CoV-2 by real-time RT-PCR. Environmental survey was performed. The epidemiological and clinical characteristics of the SSE were studied.

resultsPatient 1 with congestive heart failure and cellulitis, who had onset of COVID-19 two weeks after hospitalization, was the index case. Patient 1 led to 8 confirmed cases, including four health care workers (HCW). Persons tested positive for SARS-CoV-2 were HCW (n = 4), patient 1's family (n = 2), an accompanying person of an un-infected in-patient (n = 1), and an in-patient admitted before the SSE (n = 1). The attack rate among the HCW was 3.2 % (4/127). Environmental survey confirmed contamination at the bed rails, mattresses, and sink in the room patient 1 stayed, suggesting fomite transmission. The index case's sputum remained positive on illness day 35. Except one asymptomatic patient, at least three patients acquired the infection from the index case at the pre-symptomatic period. The effective reproduction number (R

conclusionThe host factor (heart failure, longer viral shedding), transmissibility of SARS-CoV-2 (R

Indexed as

COVID-19SARS-CoV-2Contact TracingHospitalsHumansVirus SheddingCOVID-19HospitalOutbreakSARS-CoV-2Superspreading event

Identifiers

PMID34334353
PMCPMC8294754

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.