Evidence map›Paper›PMID 34333993›Full record

ArticleCirculation research2021

The SRSF4-GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy.

Javier Larrasa-Alonso, María Villalba-Orero, Carlos Martí-Gómez, Paula Ortiz-Sánchez, Marina M López-Olañeta, M Ascensión Rey-Martín, Fátima Sánchez-Cabo, François McNicoll, Michaela Müller-McNicoll, Pablo García-Pavía and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Long noncoding RNAs in ubiquitination, protein degradation, and human diseases.Biochimica et biophysica acta. Gene regulatory mechanisms · 2024
    Review
  6. Review
  7. YTHDF1 is pivotal for maintenance of cardiac homeostasis.Journal of molecular and cellular cardiology · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Exploring the multifunctionality of SR proteins.Biochemical Society transactions · 2022
    Article
  12. Understanding Cardiac Physiological Hypertrophy in a LncRNA Way.Journal of cardiovascular translational research · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Javier Larrasa-AlonsoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
María Villalba-OreroCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
Carlos Martí-GómezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
Paula Ortiz-SánchezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
Marina M López-OlañetaCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
M Ascensión Rey-MartínCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
Fátima Sánchez-CaboCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).
François McNicollGoethe University Frankfurt, Institute of Molecular Biosciences, Frankfurt/Main, Germany (F.M., M.M.-M.).ORCID 0000-0001-5150-6245
Michaela Müller-McNicollGoethe University Frankfurt, Institute of Molecular Biosciences, Frankfurt/Main, Germany (F.M., M.M.-M.).ORCID 0000-0002-7174-8310
Pablo García-PavíaCentro de Investigación Biomédica en Red Cardiovascular (CIBERCV), Madrid, Spain (M.V.-O., P.G.-P., E.L.-P.).ORCID 0000-0002-5470-2257
Enrique Lara-PezziCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.L.-A., M.V.-O., C.M.-G., P.O.S., M.M.L.-O., M.A.R.-M., F.S.C., E.L.-P.).ORCID 0000-0002-2743-1033
Spanish National Centre for Cardiovascular Research · ESCentro de Investigación Biomédica en Red · ESGoethe University Frankfurt · DEUniversidad Francisco de Vitoria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AnimalsCells, CulturedHypertrophy, Left VentricularMaleMiceMice, Inbred C57BLMyocytes, CardiacReceptors, GlucocorticoidRNA-Binding ProteinsRNA, Long NoncodingSerine-Arginine Splicing FactorsTranscriptomeReceptors, GlucocorticoidRNA-Binding ProteinsRNA, Long NoncodingSerine-Arginine Splicing FactorsSrsf4 protein, mousecardiovascular diseaseglucocorticoid receptorleft ventricular hypertrophylong noncoding RNARNA-binding proteins

Identifiers

PMID34333993
PMCPMC8409900
OpenAlexW3188285277

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.