Evidence map›Paper›PMID 34333962›Full record

ArticleHaematologica2021

Impact of cytogenetic abnormalities on outcomes of adult Philadelphia-negative acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation: a study by the Acute Leukemia Working Committee of the Center for International Blood and Marrow Transplant Research.

Aleksandr Lazaryan, Michelle Dolan, Mei-Jie Zhang, Hai-Lin Wang, Mohamed A Kharfan-Dabaja, David I Marks, Nelli Bejanyan, Edward Copelan, Navneet S Majhail, Edmund K Waller and 62 more

Registry-linked trialAbstract readPublished Erratum
In one paragraph

Article in Haematologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06175702 (Treatment Protocol for Newky Diagnosed Adult Ph-Chromosome Positive), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06175702 not yet recruitingnot on this mapstarted 2023, after this paper: background citation

Treatment Protocol for Newky Diagnosed Adult Ph-Chromosome Positive (BCR::ABL1) Acute Lymphoblastic Leukemia (LALPh2022)

TypeobservationalSponsorPETHEMA FoundationRan2023 to 2030Enrolled150ConditionsLymphoblastic Leukemia, Philadelphia-Positive ALL, Adult ALLArmsVincristine, Dexamethasone, Imatinib, Cytarabine, Mercaptopurine
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Coagulation and Fibrinolysis Dysregulation in β-Thalassemia Major: Potential Impact of Splenectomy and Medications on Thrombotic Risk.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

72 authors.

Aleksandr LazaryanH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Michelle DolanUniversity of Minnesota Medical Center, Minneapolis, MN, USA.
Mei-Jie ZhangCIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA Division of Biostatistics, Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI, USA.
Hai-Lin WangCIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Mohamed A Kharfan-DabajaDivision of Hematology-Oncology, Blood and Marrow Transplantation Program, Mayo Clinic, Jacksonville, FL, USA.
David I MarksAdult Bone Marrow Transplant, University Hospitals Bristol NHS Trust, Bristol, UK.
Nelli BejanyanDepartment of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL, USA.
Edward CopelanLevine Cancer Institute, Atrium Health, Carolinas HealthCare System, Charlotte, NC, USA.
Navneet S MajhailBlood and Marrow Transplant Program, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA.
Edmund K WallerDepartment of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Nelson ChaoDivision of Cell Therapy and Hematology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Tim PrestidgeBlood and Cancer Centre, Starship Children's Hospital, Auckland, New Zealand.
Taiga NishihoriDepartment of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Partow KebriaeiDepartment of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, TX, USA.
Yoshihiro InamotoDivision of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Betty HamiltonBlood and Marrow Transplant Program, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA.
Shahrukh K HashmiDepartment of Internal Medicine, Mayo Clinic, MN, USA; Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Rammurti T KambleDivision of Hematology and Oncology, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Ulrike BacherDepartment of Hematology, Inselspital, Bern University Hospital, Switzerland.
Gerhard C HildebrandtMarkey Cancer Center, University of Kentucky, Lexington, KY, USA.
Patrick J StiffLoyola University Medical Center, Maywood, IL, USA.
Joseph McGuirkUniversity of Kansas Medical Center, Westwood, KS, USA.
Ibrahim AldossCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Amer M BeitinjanehUniversity of Miami, Miami, FL, USA.
Lori MufflyDivision of Blood and Marrow Transplantation, Stanford University, Stanford, CA, USA.
Ravi VijDivision of Hematology and Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Richard F OlssonDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Clinical Research Sormland, Uppsala University, Uppsala, Sweden.
Michael ByrneVanderbilt University Medical Center, Nashville, TN, USA.
Kirk R SchultzDepartment of Pediatric Hematology, Oncology and Bone Marrow Transplant, British Columbia's Children's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.
Mahmoud AljurfOncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Matthew SeftelDepartment of Medical Oncology and Hematology, CancerCare Manitoba, Winnipeg, Manitoba, Canada.
Mary Lynn SavoieTom Baker Cancer Centre, Calgary, Alberta, Canada.
Bipin N SavaniDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Leo F VerdonckDepartment of Hematology/Oncology, Isala Clinic, Zwolle, the Netherlands.
Mitchell S CairoDivision of Pediatric Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, New York Medical College, Valhalla, NY, USA.
Nasheed HossainLoyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
Vijaya Raj BhattThe Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
Haydar A FrangoulThe Children's Hospital at TriStar Centennial and Sarah Cannon Research Institute, Nashville, TN, USA.
Hisham Abdel-AzimDivision of Hematology, Oncology and Blood and Marrow Transplantation, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Monzr Al MalkiCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Reinhold MunkerSection of Hematology/Oncology, Department of Internal Medicine, Louisiana State University Health Shreveport, Shreveport, LA, USA.
David RizzieriDivision of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC, USA.
Nandita KheraDepartment of Hematology/Oncology, Mayo Clinic, Phoenix, AZ, USA.
Ryotaro NakamuraDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA.
Olle RingdénTranslational Cell Therapy Group, CLINTEC (Clinical Science, Intervention and Technology), Karolinska Institutet, Stockholm Sweden.
Marjolein Van der PoelAcademische Ziekenhuis Maastricht, Maastricht, the Netherlands.
Hemant S MurthyMayo Clinic Florida, Jacksonville, FL, USA.
Hongtao LiuUniversity of Chicago Medicine, Chicago, IL, USA.
Shahram MoriBlood and Marrow Transplant Center, Florida Hospital Medical Group, Orlando, FL, USA.
Satiro De OliveiraUCLA Medical Center, Los Angeles, CA, USA.
Javier Bolaños-MeadeThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.
Mahmoud ElsawyQE II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada.
Pere BarbaHospital Vall d'Hebron, Barcelona, Spain.
Sunita NathanRush University Medical Center, Chicago, IL, USA.
Biju GeorgeChristian Medical College, Vellore, India.
Attaphol PawarodeBlood and Marrow Transplantation Program, Division of Hematology/Oncology, Department of Internal Medicine, The University of Michigan Medical School, Ann Arbor, MI, USA.
Michael GrunwaldDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
Vaibhav AgrawalDivision of Hematology- Oncology, Indiana University School of Medicine, Indianapolis, IN, USA.
Youjin WangNational Cancer Institute (NCI), Rockville, MD, USA.
Amer AssalNew York Presbyterian Hospital/Columbia University Medical Center, New York, NY, USA.
Paul Castillo CaroUF Health Shands Children's Hospital, Gainesville, FL, USA.
Yachiyo KuwatsukaDepartment of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
Sachiko SeoDepartment of Hematology and Oncology, Dokkyo Medical University, Tochigi, Japan.
Celalettin UstunDivision of Hematology/Oncology/Cell Therapy, Rush University, Chicago, IL, USA.
Ioannis PolitikosMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Hillard M LazarusCase Western Reserve University, Cleveland, OH, USA.
Wael SaberCIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Brenda M SandmaierDivision of Medical Oncology, University of Washington and Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Marcos De LimaDepartment of Medicine, Seidman Cancer Center, University Hospitals Case Medical Center, Cleveland, OH, USA.
Mark LitzowDivision of Hematology and Transplant Center, Mayo Clinic Rochester, Rochester, MN, USA.
Veronika BachanovaBlood and Marrow Transplant Program, University of Minnesota Medical Center, Minneapolis, MN, USA.
Daniel WeisdorfDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA; CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcutePrecursor Cell Lymphoblastic Leukemia-LymphomaAdultChromosome AberrationsHumans

Identifiers

PMID34333962
PMCPMC8327734

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.