ArticleTropical animal health and production2021
Landscape genomics and selection signatures of local adaptation of Eritrean indigenous cattle along environmental gradients.
Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 5 citations in OpenAlex.
- Integrating whole-genome resequencing data reveals adaptive selection signatures under extreme environments of goat populations in China.BMC genomics · 2026Article
- Gene expression and dispersion profiles associated with water consumption and general activity in grazing beef cattle.Tropical animal health and production · 2025Article
- Integrating SNP data to reveal the adaptive selection features of goat populations in extreme environments.BMC genomics · 2025Article
- Landscape genomics reveals regions associated with adaptive phenotypic and genetic variation in Ethiopian indigenous chickens.BMC genomics · 2024Article
- Comparative genomic analysis uncovers candidate genes related with milk production and adaptive traits in goat breeds.Scientific reports · 2023Article
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4 authors at 2 institutions in 1 country.
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Abstract
Most parts of Eritrea are classified as arid and semi-arid land (ASALs) which are characterised by dryness, high ambient temperatures and low precipitation. The country has three different environmental landscapes: highland, Western lowland and Eastern lowland agro-ecological zones (AEZs). The geophysical and biophysical characteristics of the AEZs vary. Indigenous cattle which are mainly kept in extensive production system have to cope with the adverse climatic conditions of these AEZs. They have to adapt to the harsh climate, poor feed quality and endemic diseases and parasites and reproduction challenges in the AEZs. The underlying genetic basis of the indigenous cattle adaption to the specific AEZs in Eritrea is limited. In this study, it is hypothesized that the indigenous cattle have evolved and developed unique adaptive characteristics because of being reared in specific ecological landscapes. This was tested using the landscape genomics and analysis of selection signatures to ascertain the genetic basis of their adaptability to the nutritional and environmental constraints that characterise the AEZ conditions. The study was carried out in three different environmental landscapes: highland, Eastern lowland and Western lowland AEZs. Blood samples were collected from a total of 188 indigenous cattle populations sampled from the three AEZs. DNA was extracted and genotyped using the genotype by sequencing (GBS) method. Analysis revealed the existence of medium to high genetic diversity between and within the indigenous cattle populations. Scanning of selection signatures revealed genomic regions under positive selection. The regions harboured genes (IFNAR2, CASR, AHSG, ATP1B3, AIRE, ROBO2, SCHIP1 and PARS2) of importance for facial morphology, locomotion, mineral homeostasis, immune system and skeletal and muscle system development. Findings pointed out the influence of AEZ landscapes on the genetic differentiation of indigenous cattle appearances probably due to selection driven by diverse climatic and biophysical conditions. The differentiation is orientated towards adaptive characteristics.
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