Evidence map›Paper›PMID 34333389›Full record

Observational studyRespiratory medicine2021

Usefulness of the HACOR score in predicting success of CPAP in COVID-19-related hypoxemia.

Miguel Filipe Guia, José Pedro Boléo-Tomé, Pasquale Imitazione, Giorgio Emanuele Polistina, Carlos Alves, Oki Ishikawa, Matthew Ballenberger, Bushra Mina, Giuseppe Fiorentino, Antonio Esquinas and 1 more

Open access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Respiratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Early Prediction of High-flow Nasal Cannula Failure Using Pediatric-modified HACOR Score in Children with Acute Hypoxemic Respiratory Distress: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
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  2. Review
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  4. Longitudinal Assessment of ROX and HACOR Scores to Predict Non-Invasive Ventilation Failure in Patients with SARS-CoV-2 Pneumonia.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024
    Article
  5. Hail the HACOR as a Customized Indian Weaning Score!Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
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  8. Review
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  10. Heart Rate, Acidosis, Consciousness, Oxygenation, and Respiratory Rate: A Perfect Weaning Index or Just a New Kid on the Block.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Miguel Filipe GuiaPulmonology Department, Hospital Prof. Doutor Fernando Fonseca; IC19, 2720-276 Amadora, Portugal. Electronic address: miguelguia7@gmail.com.
José Pedro Boléo-ToméPulmonology Department, Hospital Prof. Doutor Fernando Fonseca; IC19, 2720-276 Amadora, Portugal.
Pasquale ImitazionePulmonology Department, Monaldi Hospital, Via Leonardo Bianchi, 80131 Naples, Italy.
Giorgio Emanuele PolistinaPulmonology Department, Monaldi Hospital, Via Leonardo Bianchi, 80131 Naples, Italy.
Carlos AlvesPulmonology Department, Hospital Prof. Doutor Fernando Fonseca; IC19, 2720-276 Amadora, Portugal.
Oki IshikawaPulmonary Critical Care Division, Lung Center, Northwell/Lenox Hill Hospital, 100 E 77th St., New York, USA.
Matthew BallenbergerPulmonary Critical Care Division, Lung Center, Northwell/Lenox Hill Hospital, 100 E 77th St., New York, USA.
Bushra MinaPulmonary Critical Care Division, Lung Center, Northwell/Lenox Hill Hospital, 100 E 77th St., New York, USA.
Giuseppe FiorentinoPulmonology Department, Monaldi Hospital, Via Leonardo Bianchi, 80131 Naples, Italy.
Antonio EsquinasIntensive Care Unit, Morales Meseguer Hospital; Av Marqués de Los Vélez, S/n, 30008 Murcia, Spain.
Raffaele ScalaPulmonology Department and Respiratory Intensive Care Unit, San Donato Hospital; Via Pietro Nenni, 20/22, 52100 Arezzo, Italy.
Hospital Prof. Dr. Fernando Fonseca · PTLenox Hill Hospital · USOspedale Monaldi · ITHospital General Universitario Morales Meseguer · ESOspedale San Donato · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn COVID-19 associated hypoxemic acute respiratory failure (ARF) without mandatory indication for urgent endotracheal intubation, a trial of CPAP may be considered. We aimed to evaluate HACOR (heart rate, acidosis, consciousness, oxygenation, respiratory rate) score performance in these patients as predictor of CPAP failure.

methodsProspective observational multicentric study (three centers in different countries), including adult patients with SARS-CoV-2 pneumonia admitted to a respiratory intermediate care unit, presenting PaO

resultsWe enrolled 128 patients, mean age 61,7 years. Mean HACOR at 1 h after starting CPAP was 3,27 ± 3,84 and mean PaO

conclusionAlthough HACOR score had a good diagnostic performance in predicting CPAP failure in COVID-19-related ARF, PaO

Indexed as

Continuous Positive Airway PressureAcidosisAgedBlood Gas AnalysisConsciousnessCOVID-19FemaleHeart RateHumansIntubation, IntratrachealMaleMiddle AgedPredictive Value of TestsProspective StudiesRespiratory InsufficiencyRespiratory RateCOVID-19CPAPHACOR scoreHypoxemic acute respiratory failure

Identifiers

PMID34333389
PMCPMC8313899
OpenAlexW3185424993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.