Evidence map›Paper›PMID 34333242›Full record

ArticleGait & posture2021

Is the dynamic gait index a useful outcome to measure balance and ambulation in patients with cerebellar ataxia?

Rachel Reoli, Amanda Therrien, Kendra Cherry-Allen, Jennifer Keller, Jennifer Millar, Amy Bastian

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gait & posture, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Rachel ReoliDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA; Department of Rehabilitation Sciences, University of Maryland Baltimore, Baltimore, MD, USA; Center for Movement Studies, Kennedy Krieger Institute, Baltimore, MD, USA. Electronic address: rreoli1@jhmi.edu.
Amanda TherrienMoss Rehabilitation Research Institute, Elkins Park, PA, USA.
Kendra Cherry-AllenDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Jennifer KellerCenter for Movement Studies, Kennedy Krieger Institute, Baltimore, MD, USA.
Jennifer MillarDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Amy BastianDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA; Center for Movement Studies, Kennedy Krieger Institute, Baltimore, MD, USA; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Johns Hopkins Hospital · USJohns Hopkins University · USKennedy Krieger Institute · USMoss Rehabilitation Hospital · USUniversity of Maryland, Baltimore · US

Funding

Research Training in Rehabilitation for Brain Injury and Neurological DisabilityT32HD007414 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Amy J. Bastian · 1991 to 2026
$6.3M
MECHANISMS AND REHABILITATION OF CEREBELLAR ATAXIAR01HD040289 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BASTIAN, AMY J. · 2002 to 2022
$6.2M
NICHD NIH HHS R01 HD040289NICHD NIH HHS T32 HD007414
6 · The paper itself

Abstract

backgroundAtaxia can adversely affect balance and gait and increase the incidence of falls, which puts individuals at greater risk for injury. Thus, interventions focused on balance and gait are integral in rehabilitation training. In order to determine if rehabilitation interventions are effective, we need an outcome measure to detect change. To our knowledge, no activity level outcome measures have been established for balance and gait in cerebellar ataxia.

objectiveThe aim of the current study is to determine the reliability and validity of the Dynamic Gait Index (DGI) for ataxia.

designTwenty adult participants (23-84 years) with ataxia were evaluated to assess construct validity, inter-rater reliability, and same day test-retest reliability of the DGI.

methodsParticipants completed ataxia-specific impairment level outcome measures, as well as the DGI. In addition to the in-person rater, three additional physical therapists scored video recordings of DGI test and retests. Construct validity was assessed via Spearman's rank order correlation coefficient (Spearman's rho) between the impairment measures (Scale for Assessment and Rating of Ataxia (SARA), International Cooperative of Ataxia Rating Scale (ICARS) and the DGI. Reliability was assessed by Spearman's rho and Intraclass Correlation Coefficient ICC (2,1).

resultsIn terms of construct validity, we found significant correlations between the activity level DGI and impairment level outcome measures (-0.81 for SARA; -0.88 with ICARS). The interrater reliability of the DGI applied to participants with ataxia was high (Spearman rho: range 0.71-0.98; ICC (2,1) 0.98) as was test-retest reliability (Spearman rho: 0.95; ICC (2,1) 0.98).

conclusionWe showed that the DGI is a reliable and valid outcome measure to be used in the clinic for individuals with cerebellar ataxia. The DGI had excellent inter-rater and test-retest reliability for raters with varying years of clinical experience. Therefore, the DGI can be a useful clinical outcome measure for assessing balance and ambulation for individuals with cerebellar ataxia.

Indexed as

Cerebellar AtaxiaWalkingAdultAgedAged, 80 and overGaitHumansMiddle AgedPostural BalanceReproducibility of ResultsYoung AdultAtaxiaBalanceDynamic gait indexGaitOutcome measures

Identifiers

PMID34333242
PMCPMC8449807
OpenAlexW3185719019

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.