Evidence map›Paper›PMID 34332876›Full record

ArticleJACC. Clinical electrophysiology2021

Diabetes and Risk of Sudden Death in Coronary Artery Disease Patients Without Severe Systolic Dysfunction.

Ramkumar V Venkateswaran, M V Moorthy, Neal A Chatterjee, Julie Pester, Alan H Kadish, Daniel C Lee, Nancy R Cook, Christine M Albert

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Clinical electrophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01114269 (PRE-DETERMINE), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01114269 active not recruitingnot on this map

PRE-DETERMINE: Biologic Markers and MRI SCD Cohort Study

TypeobservationalSponsorBrigham and Women's HospitalRan2007 to 2026Enrolled5,764ConditionsCoronary Artery Disease, Left Ventricular Dysfunction, Sudden Cardiac Death
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Sudden cardiac death in stable coronary artery disease: A literature review.American heart journal plus : cardiology research and practice · 2026
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Ramkumar V VenkateswaranDivision of Cardiology, University of California-San Francisco, San Francisco, California, USA.
M V MoorthyDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Neal A ChatterjeeDivision of Cardiology, University of Washington, Seattle, Washington, USA.
Julie PesterDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Alan H KadishTouro College and University System, New York, New York, USA.
Daniel C LeeDivision of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Nancy R CookDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Christine M AlbertDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. Electronic address: Christine.albert@cshs.org.
Brigham and Women's Hospital · USNorthwestern University · USTouro College · USUniversity of California, San Francisco · USUniversity of Washington · US

Funding

PRE-DETERMINE: Biologic Markers and MRI SCD Cohort StudyR01HL091069 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ALBERT, CHRISTINE M · 2008 to 2020
$12.9M
NHLBI NIH HHS R01 HL091069
6 · The paper itself

Abstract

objectivesThis study sought to determine the absolute and relative associations of diabetes mellitus (DM) and hemoglobin A

backgroundPatients with CAD and DM are at elevated risk for SAD; however, it is unclear whether these patients would benefit from implantable cardioverter-defibrillators given competing causes of death and/or whether HbA

methodsIn the PRE-DETERMINE study of 5,764 patients with CAD with left ventricular ejection fraction (LVEF) of >30% to 35%, competing risk analyses were used to compare the absolute and relative risks of SAD versus non-SAD by DM status and HbA

resultsOver a median follow-up of 6.8 years, DM and HbA

conclusionsIn patients with CAD and LVEF of >30% to 35%, patients with DM and/or elevated HbA

Indexed as

Coronary Artery DiseaseDiabetes MellitusCohort StudiesDeath, Sudden, CardiacHumansStroke VolumeVentricular Function, Leftdiabetes mellitusHbA(1c)risk stratificationsudden cardiac death

Identifiers

PMID34332876
PMCPMC8788939
OpenAlexW3185573017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.