ArticleTrials2021
REBOARREST, resuscitative endovascular balloon occlusion of the aorta in non-traumatic out-of-hospital cardiac arrest: a study protocol for a randomised, parallel group, clinical multicentre trial.
Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised Trial on Resuscitative Endovascular Balloon Occlusion of the Aorta in Non-traumatic Out of Hospital Cardiac Arrest
Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Pooled it
- Resuscitative endovascular balloon occlusion of the aorta in civilian pre-hospital care: a systematic review of the literature.European journal of medical research · 2022Pooled it
- Prehospital resuscitative endovascular balloon occlusion of the aorta in non-traumatic out-of-hospital cardiac arrest (REBOARREST): an international, multicentre, open label, pragmatic, randomised, controlled trial.Critical care (London, England) · 2026Trial
- Trial
- Endovascular resuscitation: an expert practice review.Emergency medicine journal : EMJ · 2026Review
- Authors' response: balloon size and interpretation of the REBOARREST trial.Critical care (London, England) · 2026Article
- Article
- Physiological changes after deflation of Resuscitative Endovascular Balloon Occlusion of the Aorta following Automated Head-up Position Cardiopulmonary Resuscitation: a post-hoc analysis.Resuscitation plus · 2026Article
- Resuscitation 2025 congress: launch of the resuscitation guidelines, scientific advances, education, equity, and innovation across the chain of survival.Resuscitation plus · 2026Article
- Feasibility of REBOA (Resuscitative Endovascular Balloon Occlusion of the Aorta) Implementation in HEMS (Helicopter Emergency Medical Service) Units in Castilla-La Mancha, Spain.Nursing reports (Pavia, Italy) · 2026Article
- [Resuscitative endovascular balloon occlusion of the aorta-REBOA for bleeding control in the prehospital context : Overview of available cases and evaluation of the evidence].Die Anaesthesiologie · 2025Review
- Use of resuscitative endovascular balloon occlusion of the aorta in ruptured pseudoaneurysm after simultaneous pancreas-kidney transplantation.Journal of vascular surgery cases and innovative techniques · 2025Article
- Femoral Vessel Occlusion Enhances Cardiac and Cerebral Perfusion in a Porcine Model of Cardiac Arrest.Journal of the American Heart Association · 2025Article
- Balloon occlusion of the aorta during cardiac arrest -a death blow to the intestines?Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Article
- Article
- Resuscitative Endovascular Balloon Occlusion of the Aorta in surgical and trauma patients: a systematic review, meta-analysis and practice management guideline from the Eastern Association for the Surgery of Trauma.Trauma surgery & acute care open · 2025Article
- Feasibility of a 4 French resuscitative endovascular balloon occlusion of the aorta (REBOA) device for nontraumatic cardiac arrest in a randomized controlled study using a large porcine model.Resuscitation plus · 2024Article
- A protocol for the ERICA-ARREST feasibility study of Emergency Resuscitative Endovascular Balloon occlusion of the Aorta in Out-of-Hospital Cardiac Arrest.Resuscitation plus · 2024Article
- Current trends in the management of out of hospital cardiac arrest (OHCA).Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2024Review
- The detrimental effects of intestinal injury mediated by inflammation are limited in cardiac arrest patients: A prospective cohort study.Resuscitation plus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurvival after out-of-hospital cardiac arrest (OHCA) is poor and dependent on high-quality cardiopulmonary resuscitation. Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be advantageous in non-traumatic OHCA due to the potential benefit of redistributing the cardiac output to organs proximal to the aortic occlusion. This theory is supported by data from both preclinical studies and human case reports.
methodsThis multicentre trial will enrol 200 adult patients, who will be randomised in a 1:1 ratio to either a control group that receives advanced cardiovascular life support (ACLS) or an intervention group that receives ACLS and REBOA. The primary endpoint will be the proportion of patients who achieve return of spontaneous circulation with a duration of at least 20 min. The secondary objectives of this trial are to measure the proportion of patients surviving to 30 days with good neurological status, to describe the haemodynamic physiology of aortic occlusion during ACLS, and to document adverse events. DISCUSSION: Results from this study will assess the efficacy and safety of REBOA as an adjunctive treatment for non-traumatic OHCA. This novel use of REBOA may contribute to improve treatment for this patient cohort.
trial registrationThe trial is approved by the Regional Committee for Medical and Health Research Ethics in Norway (reference 152504) and is registered at ClinicalTrials.gov (reference NCT04596514) and as Universal Trial Number WHO: U1111-1253-0322.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.