ArticleDevelopmental cognitive neuroscience2021
Is executive dysfunction a risk marker or consequence of psychopathology? A test of executive function as a prospective predictor and outcome of general psychopathology in the adolescent brain cognitive development study®.
Article in Developmental cognitive neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- The clinical relevance of healthy neurodevelopmental connectivity in childhood and adolescence: a meta-analysis of resting-state fMRI.Frontiers in neuroscience · 2025Pooled it
- Digital goal management training for cognitive impairment in cervical cancer survivors-a randomized comparison study.Journal of cancer survivorship : research and practice · 2026Trial
- Randomized Feasibility Pilot of an Executive Functioning Intervention Adapted for Children's Mental Health Settings.Journal of autism and developmental disorders · 2025Trial
- A randomized controlled trial of Goal Management Training for executive functioning in schizophrenia spectrum disorders or psychosis risk syndromes.BMC psychiatry · 2022Trial
- Executive functions as a transdiagnostic endophenotype in developmental psychopathology.Molecular psychiatry · 2026Review
- Cerebellar Functional Alterations During Executive Functioning Are Associated With General Psychopathology in a Cross-Diagnostic Sample.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Examining early inhibitory control and emotion regulation as predictors of childhood internalizing and externalizing problems: A longitudinal study.JCPP advances · 2026Article
- Early‑life head circumference is causally associated with adult executive function through cortical surface area expansion.Developmental cognitive neuroscience · 2026Article
- Is Bedtime Procrastination Related to Multidimensional Sleep Health? Evidence from Samples of Different Educational Stages (Aged 10-25) in China.Child psychiatry and human development · 2026Article
- Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study.Developmental cognitive neuroscience · 2026Review
- Interrogating cognitive and neural group variation in childhood: Examples in adolescent brain cognitive development and Oregon attention-deficit/hyperactivity disorder-1000 cohorts.Journal of psychopathology and clinical science · 2026Article
- Associations Among Bullying Victimization, Executive Functions, and Adolescent Internalizing and Externalizing Symptoms: A Random-Intercept Cross-Lagged Panel Model.Journal of adolescence · 2026Article
- Behavior Regulation Abilities in Children With Prader-Willi Syndrome and Their Impact on Daily Life: At the Crossroads of Cognitive and Emotional Development.Journal of autism and developmental disorders · 2026Article
- Development of internalizing symptomology in harsh rearing and neighborhood contexts: The role of executive functioning.Developmental psychology · 2026Article
- Alterations in resting-state functional connectivity relate to psychopathology trajectories during emerging adolescence.JCPP advances · 2026Article
- Executive function and implications for the Preterm Behavioral Phenotype in very preterm children at age 9-10 years.Journal of neurodevelopmental disorders · 2026Article
- From childhood psychological maltreatment to fear of happiness: the parallel mediating roles of self-concept clarity and executive function.BMC psychology · 2026Article
- Disorder-Specific Genetic Effects Drive the Associations Between Psychopathology and Cognitive Functioning.Biological psychiatry global open science · 2026Article
- Executive Dysfunction and Depression Risk in Adolescence: Functional-MRI Analysis of Transient Network States During a Working Memory Task.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Psychopathology profiles and longitudinal correlates of nonsuicidal self-injury in youth: a machine-learning approach.Translational psychiatry · 2026Article
22 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A general psychopathology ('p') factor captures shared variation across mental disorders. One hypothesis is that poor executive function (EF) contributes to p. Although EF is related to p concurrently, it is unclear whether EF predicts or is a consequence of p. For the first time, we examined prospective relations between EF and p in 9845 preadolescents (aged 9-12) from the Adolescent Brain Cognitive Development Study® longitudinally over two years. We identified higher-order factor models of psychopathology at baseline and one- and two-year follow-up waves. Consistent with previous research, a cross-sectional inverse relationship between EF and p emerged. Using residualized-change models, baseline EF prospectively predicted p factor scores two years later, controlling for prior p, sex, age, race/ethnicity, parental education, and family income. Baseline p factor scores also prospectively predicted change in EF two years later. Tests of specificity revealed that bi-directional prospective relations between EF and p were largely generalizable across externalizing, internalizing, neurodevelopmental, somatization, and detachment symptoms. EF consistently predicted change in externalizing and neurodevelopmental symptoms. These novel results suggest that executive dysfunction is both a risk marker and consequence of general psychopathology. EF may be a promising transdiagnostic intervention target to prevent the onset and maintenance of psychopathology.
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