ArticleJournal of biomechanics2021
Pilot evaluation of changes in motor control after wearable robotic resistance training in children with cerebral palsy.
Article in Journal of biomechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05330052 (The Effects of a Powered Knee Orthosis on Gait Kinematics of Children With Knee Extension Deficiency), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of a Powered Knee Orthosis on Gait Kinematics of Children With Knee Extension Deficiency
Who cites it
19 citing papers in PubMed.
- A scoping review of the application scope of digital technologies in lower limb rehabilitation and balance training for children with cerebral palsy.Frontiers in pediatrics · 2026Review
- Wearable Robots for Rehabilitation and Assistance of Gait: A Narrative Review.Annals of rehabilitation medicine · 2025Article
- Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?Journal of neuroengineering and rehabilitation · 2025Article
- Advancing Gait Rehabilitation: A Systematic Review of Robotic Exoskeletons for Cerebral Palsy.Wearable technologies · 2025Review
- Muscle Synergy Analysis as a Tool for Assessing the Effectiveness of Gait Rehabilitation Therapies: A Methodological Review and Perspective.Bioengineering (Basel, Switzerland) · 2024Review
- DE-AFO: A Robotic Ankle Foot Orthosis for Children with Cerebral Palsy Powered by Dielectric Elastomer Artificial Muscle.Sensors (Basel, Switzerland) · 2024Article
- Does crouch alter the effects of neuromuscular impairments on gait? A simulation study.Journal of biomechanics · 2024Article
- An analysis of stimulation methods used in rehabilitation equipment for children with cerebral palsy.Frontiers in neurology · 2024Review
- Exoskeleton gait training on real-world terrain improves spatiotemporal performance in cerebral palsy.Frontiers in bioengineering and biotechnology · 2024Article
- Multi-session adaptation to audiovisual and sensorimotor biofeedback is heterogeneous among adolescents with cerebral palsy.PloS one · 2024Article
- Audiovisual biofeedback amplifies plantarflexor adaptation during walking among children with cerebral palsy.Journal of neuroengineering and rehabilitation · 2023Article
- Factors influencing neuromuscular responses to gait training with a robotic ankle exoskeleton in cerebral palsy.Assistive technology : the official journal of RESNA · 2023Article
- Enhancing Post-Operative Recovery in Spastic Diplegia through Physical Therapy Rehabilitation following Selective Dorsal Rhizotomy: A Case Report and Thorough Literature Analysis.Children (Basel, Switzerland) · 2023Article
- Motor control complexity can be dynamically simplified during gait pattern exploration using motor control-based biofeedback.Journal of neurophysiology · 2023Article
- Mechanical disturbances applied by motorized ankle foot orthosis to adapt ankle muscles activation-A validation study.Frontiers in bioengineering and biotechnology · 2023Article
- Causal modelling demonstrates metabolic power is largely affected by gait kinematics and motor control in children with cerebral palsy.PloS one · 2023Article
- Soleus H-reflex modulation in cerebral palsy and its relationship with neural control complexity: a pilot study.Experimental brain research · 2022Article
- Synergies are minimally affected during emulation of cerebral palsy gait patterns.Journal of biomechanics · 2022Article
- Promoting child and adolescent health through wearable technology: A systematic review.Digital healthReview
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Cerebral palsy (CP) is characterized by deficits in motor function due to reduced neuromuscular control. We leveraged the guiding principles of motor learning theory to design a wearable robotic intervention intended to improve neuromuscular control of the ankle. The goal of this study was to determine the neuromuscular and biomechanical response to four weeks of exoskeleton ankle resistance therapy (exo-therapy) in children with CP. Five children with CP (12 - 17 years, GMFCS I - II, two diplegic and three hemiplegic, four males and one female) were recruited for ten 20-minute sessions of exo-therapy. Surface electromyography, three-dimensional kinematics, and metabolic data were collected at baseline and after training was complete. After completion of training and with no device on, participants walked with decreased co-contraction between the plantar flexors and dorsiflexors (-29 ± 11%, p = 0.02), a more typical plantar flexor activation profile (33 ± 13% stronger correlation to a typical soleus activation profile, p = 0.01), and increased neural control complexity (7 ± 3%, p < 0.01 measured via muscle synergy analysis). These improvements in neuromuscular control led to a more mechanically efficient gait pattern (58 ± 34%, p < 0.05) with a reduced metabolic cost of transport (-29 ± 15%, p = 0.02). The findings from this study suggest that ankle exoskeleton resistance therapy shows promise for rapidly improving neuromuscular control for children with CP, and may serve as a meaningful rehabilitative complement to common surgical procedures.
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