Evidence map›Paper›PMID 34331977›Full record

Observational studyDiabetes research and clinical practice2021

Has COVID-19 lockdown improved glycaemic control in pediatric patients with type 1 diabetes? An analysis of continuous glucose monitoring metrics.

Fortunato Lombardo, Giuseppina Salzano, Bruno Bombaci, Pietro Basile, Giovanni Lucania, Angela Alibrandi, Stefano Passanisi

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Diabetes research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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  11. Endocrine manifestations of COVID-19 in children: A scoping review.Best practice & research. Clinical endocrinology & metabolism · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fortunato LombardoDepartment of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy.
Giuseppina SalzanoDepartment of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy. Electronic address: stepassanisi@unime.it.
Bruno BombaciDepartment of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy.
Pietro BasileDepartment of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy.
Giovanni LucaniaDepartment of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy.
Angela AlibrandiDepartment of Economics, Unit of Statistical and Mathematical Sciences, University of Messina, Messina, Italy.
Stefano PassanisiDepartment of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy.
University of Messina · ITIstituto Ortopedico Gaetano Pini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsOur observational study aimed to evaluate the impact of the lockdown period due to 2019 Coronavirus disease pandemic on glycaemic control in a cohort of paediatric patients with type 1 diabetes (T1D).

methodsEighty-five patients with T1D aged 5-18 years using continuous glucose monitoring (CGM) systems were enrolled. Demographic and clinical data, including glucose metrics generated by CGM-specific web-based cloud platforms, were collected in three different periods (pre-lockdown phase, lockdown phase, and post-lockdown phase) of 90 days each and were statistically analysed.

resultsDuring the lockdown period, a clear improvement in almost all CGM metrics (time in range, time above range, coefficient of variation, and glucose management indicator) was observed in our study population, regardless of age and insulin type treatment. In the months following lockdown, maintaining satisfactory diabetes outcomes was confirmed only in younger patients (aged 5-9 years) and in those individuals on hybrid closed loop therapy.

conclusionsThe increasing use of innovative technological devices together with data sharing systems and interaction with multidisciplinary diabetes team through telemedicine allowed paediatric patients with T1D to improve glucose metrics during the lockdown period. However, our findings showed that the achievement of better glycaemic control was transient for most patients.

Indexed as

Communicable Disease ControlCOVID-19Diabetes Mellitus, Type 1Glycemic ControlAdolescentBlood GlucoseBlood Glucose Self-MonitoringChildChild, PreschoolFemaleHumansHypoglycemic AgentsMaleBlood GlucoseHypoglycemic AgentsAdolescenceAmbulatory glucose profileChildrenHybrid closed loopPandemicTime in range

Identifiers

PMID34331977
PMCPMC8416096
OpenAlexW3184472062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.