Evidence map›Paper›PMID 34331958›Full record

ArticlePhysiology & behavior2021

Targeting executive function for weight loss in adults with overweight or obesity.

Dawn M Eichen, Ellen K Pasquale, Elizabeth W Twamley, Kerri N Boutelle

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiology & behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dawn M EichenDepartment of Pediatrics, University of California San Diego, 9500 Gilman Dr, San Diego, CA 92093 USA. Electronic address: deichen@ucsd.edu.
Ellen K PasqualeDepartment of Pediatrics, University of California San Diego, 9500 Gilman Dr, San Diego, CA 92093 USA.
Elizabeth W TwamleyDepartment of Psychiatry, University of California San Diego, 9500 Gilman Dr, San Diego, CA 92093 USA; Center of Excellence for Stress and Mental Health and Research Service, VA San Diego Healthcare System, USA.
Kerri N BoutelleDepartment of Pediatrics, University of California San Diego, 9500 Gilman Dr, San Diego, CA 92093 USA; Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, San Diego, CA 92093 USA; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, 9500 Gilman Dr, San Diego, CA 92093 USA.

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Novel Executive Function Training for ObesityK23DK114480 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EICHEN, DAWN · 2018 to 2022
$995k
NCATS NIH HHS UL1 TR001442NIDDK NIH HHS K23 DK114480
6 · The paper itself

Abstract

Obesity is associated with a multitude of negative health sequalae. Behavioral weight loss (BWL) is currently the recommended behavioral treatment for obesity; however, it is not effective for approximately half of the individuals who participate. BWL requires individuals to carry out many tasks requiring executive function (EF; i.e., higher order cognitive functions such as planning and problem solving) in order to be successful. Growing research supports that lower EF may be associated with attenuated weight loss following BWL, and targeting EF in treatment could improve outcomes. This paper aims to describe the rationale for the development of Novel Executive Function Training for Obesity (NEXT), which adapts Compensatory Cognitive Training to be delivered in conjunction with BWL. We summarize evidence relating EF to obesity and reduced weight loss following BWL, as well as the past success of cognitive training on EF. Then we describe the treatment model for NEXT followed by initial data suggesting that NEXT is feasible and acceptable and may impact EF and weight. Obesity treatments incorporating cognitive training, especially those that train compensatory strategies, may improve weight-loss outcomes and provide a more durable treatment than traditional interventions, but larger randomized control trials are necessary.

Indexed as

Executive FunctionWeight LossAdultHumansObesityOverweightTreatment OutcomeCognitive trainingEating behaviorExecutive functionPhysical activityWeight loss

Identifiers

PMID34331958
PMCPMC8823407

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.