ArticleJournal of clinical hypertension (Greenwich, Conn.)2021
Day-by-day blood pressure variability in hospitalized patients with COVID-19.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Blood pressure variability and its utility in acute disease and critical illness: a systematic review.BMC anesthesiology · 2025Pooled it
- Higher intraindividual variability of body mass index is associated with elevated risk of COVID-19 related hospitalization and post-COVID conditions.International journal of obesity (2005) · 2024Article
- Systemic Immune Inflammatory Index as Predictor of Blood Pressure Variability in Newly Diagnosed Hypertensive Adults Aged 18-75.Journal of clinical medicine · 2024Article
- Perspectives of (/memorandum for) systems thinking on COVID-19 pandemic and pathology.Journal of evaluation in clinical practice · 2023Article
- Investigating autonomic nervous system dysfunction among patients with post-COVID condition and prolonged cardiovascular symptoms.Frontiers in medicine · 2023Article
- COVID-19 detection using a model of photoplethysmography (PPG) signals.Medical engineering & physics · 2022Article
- Admission vital signs as predictors of COVID-19 mortality: a retrospective cross-sectional study.BMC emergency medicine · 2022Article
- Prognostic significance of day-by-day in-hospital blood pressure variability in COVID-19 patients with hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Day-to-day blood pressure variability and severity of COVID-19: Is sympathetic overdrive a potential link?Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Day-by-day blood pressure variability in hospitalized patients with COVID-19.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
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8 authors at 1 institution in 1 country.
Funding
Abstract
In a retrospective analysis, the authors investigated day-by-day blood pressure variability (BPV) and its association with clinical outcomes (critical vs. severe and discharged) in hospitalized patients with COVID-19. The study participants were hospitalized in Tongji Hospital, Guanggu Branch, Wuhan, China, between February 1 and April 1, 2020. BPV was assessed as standard derivation (SD), coefficient of variation (CV), and variability independent of mean (VIM). The 79 participants included 60 (75.9%) severe patients discharged from the hospital after up to 47 days of hospitalization, and 19 (24.1%) critically ill patients transferred to other hospitals for further treatment (n = 13), admitted to ICU (n = 3) or died (n=3). Despite similar use of antihypertensive medication (47.4% vs. 41.7%) and mean levels of systolic/diastolic blood pressure (131.3/75.2 vs. 125.4/77.3 mmHg), critically ill patients, compared with severe and discharged patients, had a significantly (p ≤ .04) greater variability of systolic (SD 14.92 vs. 10.84 mmHg, CV 11.39% vs. 8.56%, and VIM 15.15 vs. 10.75 units) and diastolic blood pressure (SD 9.38 vs. 7.50 mmHg, CV 12.66% vs. 9.80%, and VIM 9.33 vs. 7.50 units). After adjustment for confounding factors, the odds ratios for critical versus severe and discharged patients for systolic BPV were 3.41 (95% confidence interval [CI] 1.20-9.66, p = .02), 4.09 (95% CI 1.14-14.67, p = .03), and 2.81 (95% CI 1.12-7.05, p = .03) for each 5-mmHg increment in SD, 5% increment in CV, and 5-unit increment in VIM, respectively. Similar trends were observed for diastolic BPV indices (p ≤ .08). In conclusion, in patients with COVID-19, BPV was greater and associated with worse clinical outcomes.
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