Evidence map›Paper›PMID 34331833›Full record

ArticleInternational journal of clinical practice2021

Is endogenous carboxyhaemoglobin level a useful biomarker of clinical course and prognosis in COVID-19 patients?

Buğra Kerget, Ferhan Kerget, Abdullah Osman Koçak, İlker Akbaş, Ömer Araz, Elif Yılmazel Uçar, Metin Akgün

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Is Extracorporeal Membrane Oxygenation a Panacea?The Eurasian journal of medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Buğra KergetDepartment of Pulmonary Diseases, Ataturk University School of Medicine, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-6048-1462
Ferhan KergetDepartment of Infection Diseases and Clinical Microbiology, Health Sciences University, Erzurum Regional Education and Research Hospital, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-5160-4854
Abdullah Osman KoçakDepartment of Emergency Medicine, Ataturk University School of Medicine, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-1678-4474
İlker AkbaşDepartment of Emergency Medicine, Bingöl State Hospital, Bingöl, Turkey.ORCID https://orcid.org/0000-0001-6676-6517
Ömer ArazDepartment of Pulmonary Diseases, Ataturk University School of Medicine, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-3476-4506
Elif Yılmazel UçarDepartment of Pulmonary Diseases, Ataturk University School of Medicine, Erzurum, Turkey.ORCID https://orcid.org/0000-0001-8284-1038
Metin AkgünDepartment of Pulmonary Diseases, Ataturk University School of Medicine, Erzurum, Turkey.ORCID https://orcid.org/0000-0003-3404-4274
Atatürk University · TRBingöl University · TRErzurum Regional Training and Research Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSARS-CoV-2 has caused nearly 4 million confirmed cases of COVID-19 worldwide in the approximately 4 months since it emerged in Wuhan, China in December 2019. Comorbidities increase morbidity and mortality in COVID-19, and many laboratory parameters have been associated with mortality. The aim of the present study was to identify the relationship between endogenous carboxyhaemoglobin (COHb) level and the clinical course and prognosis of COVID-19.

methodsThe study included 48 non-smokers or ex-smokers aged 18 years or older who presented to the emergency department, were diagnosed with COVID-19 by real-time PCR analysis of nasopharyngeal swab sample and were treated in the pulmonary diseases ward of the Atatürk University hospital after 24 March 2020 and 15 April 2020. The patients' laboratory parameters and demographic data were analysed retrospectively.

resultsProthrombin time and C-reactive protein (CRP), troponin-I, and D-dimer levels decreased in COVID-19 patients during follow-up (P = .024, P = .001, P = .001, P = .001), while PaO

conclusionsCOHb level may be an easily accessible biomarker that guides early follow-up and treatment planning to avoid ARDS, MAS and mortality in COVID-19.

Indexed as

CarboxyhemoglobinCOVID-19BiomarkersHumansPrognosisRetrospective StudiesSARS-CoV-2BiomarkersCarboxyhemoglobin

Identifiers

PMID34331833
PMCPMC8420518
OpenAlexW3132688983

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.