SynthesisJournal of the European Academy of Dermatology and Venereology : JEADV2021
Quality of life in patients with Mycosis Fungoides and Sézary Syndrome: a systematic review of the literature.
Synthesis in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patient-Reported Outcome Measures (PROMS) in Lymphoma.Current oncology (Toronto, Ont.) · 2025Pooled it
- Trial
- Psychological Distress, Symptom Burden and Quality of Life in Patients with Mycosis Fungoides and Sézary Syndrome.Acta dermato-venereologica · 2026Observational
- Psychological Resilience and Quality of Life in Mycosis Fungoides Patients: A BIO-MUSE Study.Acta dermato-venereologica · 2026Article
- Quality of Life in a Swedish Cohort of Patients with Mycosis Fungoides.Acta dermato-venereologica · 2026Article
- Evaluation of Sleep Disorders and Quality of Life in Patients With Mycosis Fungoides.Cancer reports (Hoboken, N.J.) · 2026Article
- The dual burden of a rare cancer: psychosocial impact of disease symptoms and unmet care needs in cutaneous T-cell lymphoma.Frontiers in psychology · 2026Article
- Chlormethine gel effectiveness as second-line treatment in mycosis fungoides: a single-centre retrospective study.Discover oncology · 2025Article
- Sexual health in older adults with hematologic malignancies - a sub-analysis of a Danish cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Economic burden and health-related quality of life in Chinese patients with mycosis fungoides and Sézary syndrome.Cancer pathogenesis and therapy · 2025Article
- Pruritus Is an Indicator for Quality of Life in Cutaneous T-Cell Lymphoma.The Journal of dermatology · 2025Article
- Family and Quality of Life Challenges in Mycosis Fungoides Patients: A Case-Control Study from Shiraz, Southern Iran.Dermatology practical & conceptual · 2025Article
- Psychosocial burden of patients with mycosis fungoides and Sézary syndrome compared to other dermatological patients. Pilot study.Postepy dermatologii i alergologii · 2025Article
- Available questionnaires do not cover important aspects of quality of life of patients with cutaneous T-cell lymphoma: evaluation of the quality of life of Polish patients with cutaneous T-cell lymphoma.Postepy dermatologii i alergologii · 2025Article
- Mental Health Diagnoses in Patients With Mycosis Fungoides and Potential Impact on Oncologic Outcomes.Cancer medicine · 2025Article
- Prevalence and Severity of Sleep Disorders in Patients With Mycosis Fungoides: A Case-Control Study.Journal of skin cancer · 2025Article
- How does mycosis fungoides affect quality of life? Comparative evaluation of the Dermatology Life Quality Index in patients with mycosis fungoides and psoriasis.Proceedings (Baylor University. Medical Center) · 2025Article
- Quality of life in mycosis fungoides.Proceedings (Baylor University. Medical Center) · 2025Article
- Identification of subgroups of early-stage mycosis fungoides patients with increased itch and impaired quality of life.Frontiers in oncology · 2025Article
- Dynamic time warp of emotions in patients with cutaneous T-cell lymphoma treated with corticosteroids.JAAD international · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Cutaneous T-cell Lymphoma's (CTCL) are a rare, heterogeneous group of T-cell lymphomas that primarily manifest in the skin. Mycosis fungoides (MF) and Sézary syndrome (SS) are considered the classic types of CTCL. The diverse manifestation of CTCL results in a wide range of symptoms with a possible mild to severe impact on Quality of Life (QoL) depending on the disease stage. Previous studies on QoL in CTCL patients report diverse patient populations and use many different QoL instruments. In the current literature, a clear overview on the influence of the different stages of disease (early MF, late-stage MF/SS or total group) on the QoL is lacking. Therefore, a systematic search of the literature was conducted using the PubMed, Embase, PsycINFO and Web of Science databases. Studies were included if they described QoL in patients with MF and SS retrieved by standardized instruments or qualitative interviews. In total, 24 studies were included using 18 different questionnaires to report on dermatology-specific, cancer-specific and generic QoL. The effect on QoL was found to be greater in patients with late-stage disease as compared to early stage disease, with significant impairments on functional, emotional and physical domains. Nonetheless, even in patients with limited disease, QoL was mildly to moderately affected. Overall, pruritus was the most frequent reported and most bothersome symptom. Significant influence of the disease on daily life activities were found, not only in patients but also on caregivers and family. This broad, structured overview on QoL in MF and SS patients underlines the influence of disease stage on QoL, and therefore, recommends future studies to distinguish between disease stages when reporting results. Furthermore, this overview can inform clinicians in clinical practice by creating awareness of QoL deficits according to disease stage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.