ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021
Health-related quality of life in children with and without physical-mental multimorbidity.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The magnitude of multimorbidity in childhood: a global systematic review.Systematic reviews · 2026Pooled it
- The association between oral health clusters and oral health-related quality of life: A population‑based study of 5‑yr‑old children.European journal of oral sciences · 2026Article
- Physical illnesses, mental or neurodevelopmental disorders, and multimorbidity in children: results from the Canadian Health Survey on Children and Youth.Social psychiatry and psychiatric epidemiology · 2026Article
- Trajectories of health-related quality of life in youth with chronic physical illness and their siblings.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Health Functioning Moderates the Association Between Chronic Conditions and Mental Illness in Childhood.Child: care, health and development · 2026Article
- Quality of Life and Mental Health Among Families Caring for Children with Medical Complexity: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Youth stress, happiness, and life satisfaction across morbidity status: a gender-stratified analysis.Scientific reports · 2026Article
- Health-Related Quality of Life and Its Association With Multimorbidity Among University Students in Jeddah, Saudi Arabia: A Cross-Sectional Study.Journal of patient experience · 2026Article
- Paediatric Patients With Multiple Referrals and Complex Health Complaints Experienced Notable Functional Impairment.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Equivalence of psychiatric structured interviews and symptom checklists in predicting health-related quality of life in children with chronic physical illness.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Trajectories of Psychopathology Among Youth with Physical Illness.Child psychiatry and human development · 2025Article
- Longitudinal Association Between Youth Multimorbidity and Psychological Distress: Impact of the COVID-19 Pandemic.Child psychiatry and human development · 2025Article
- Perceived School Belonging Among Youth with Chronic Physical Illness.Journal of psychoeducational assessment · 2024Article
- Continuity of mental disorders in children with chronic physical illness.European child & adolescent psychiatry · 2024Article
- Comparative assessment of quality of life among adolescents with sickle cell disease and sickle cell trait: evidence from Odisha, India.Journal of community genetics · 2024Article
- Response shift in parent-reported psychopathology in children with chronic physical illness.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Health-Related Quality of Life and Adherence to Physical Activity and Screen Time Recommendations in Schoolchildren: Longitudinal Cohort Ciao Corona.International journal of public health · 2023Article
- Correlates of Moderate-to-Vigorous Physical Activity in Children With Physical Illness and Physical-Mental Multimorbidity.Health education & behavior : the official publication of the Society for Public Health Education · 2022Article
- Prevalence and Correlates of Physical-mental Multimorbidity in Outpatient Children From a Pediatric Hospital in Canada.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2022Article
- The relationship between physical and mental health multimorbidity and children's health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeThis study examined health-related quality of life (HRQL) in children across different physical illnesses; estimated parent-child agreement on HRQL reports; compared HRQL between children with and without physical-mental multimorbidity; and tested if multimorbidity was associated with HRQL.
methodsChildren aged 6-16 years (mean = 11.1; n = 198) with one physical illness and their parents were recruited from a pediatric hospital. Physical illnesses were classified according to the International Statistical Classification of Diseases and Related Health Problems (ICD)-10, mental illnesses were assessed using the Mini International Neuropsychiatric Interview for Children and Adolescents, and HRQL was measured using the KIDSCREEN-27. Children who screened positive for ≥ 1 mental illness were classified as having physical-mental multimorbidity. χ
resultsHRQL was similar across ICD-10 categories. Parent-child agreement was fair to good for all HRQL domains, regardless of multimorbidity status. Parent-reported HRQL was significantly lower for children with multimorbidity compared to norms across all domains, whereas child-reported HRQL was significantly lower for physical well-being, psychological well-being, and school environment. Number of mental illnesses was negatively associated with psychological well-being and school environment in a dose-response manner.
conclusionChildren with physical-mental multimorbidity are vulnerable to experiencing lower HRQL, particularly for psychological well-being and school environment. Longitudinal studies documenting trajectories of HRQL and school-based interventions that target these domains of HRQL for children with multimorbidity are warranted.
Indexed as
Identifiers
34331638What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.