Evidence map›Paper›PMID 34331629›Full record

ArticleJournal of autism and developmental disorders2022

Brief Report: Specificity of Interpersonal Synchrony Deficits to Autism Spectrum Disorder and Its Potential for Digitally Assisted Diagnostics.

Jana Christina Koehler, Alexandra Livia Georgescu, Johanna Weiske, Moritz Spangemacher, Lana Burghof, Peter Falkai, Nikolaos Koutsouleris, Wolfgang Tschacher, Kai Vogeley, Christine M Falter-Wagner

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Social motor synchrony in autism spectrum conditions: A systematic review.Autism : the international journal of research and practice · 2024
    Pooled it
  2. Article
  3. Whole-body synchronization in autistic adults.Frontiers in human neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jana Christina Koehler *Department of Psychiatry and Psychotherapy, Medical Faculty, LMU Munich, Nussbaumstrasse 7, Munich, Germany. jana.koehler@med.uni-muenchen.de.ORCID http://orcid.org/0000-0001-7216-6075
Alexandra Livia Georgescu *Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Johanna WeiskeDepartment of Psychiatry and Psychotherapy, Medical Faculty, LMU Munich, Nussbaumstrasse 7, Munich, Germany.
Moritz SpangemacherDepartment of Psychiatry and Psychotherapy, Medical Faculty, LMU Munich, Nussbaumstrasse 7, Munich, Germany.
Lana BurghofDepartment of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Peter FalkaiDepartment of Psychiatry and Psychotherapy, Medical Faculty, LMU Munich, Nussbaumstrasse 7, Munich, Germany.
Nikolaos KoutsoulerisDepartment of Psychiatry and Psychotherapy, Medical Faculty, LMU Munich, Nussbaumstrasse 7, Munich, Germany.
Wolfgang TschacherUniversity Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Kai VogeleyDepartment of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Christine M Falter-WagnerDepartment of Psychiatry and Psychotherapy, Medical Faculty, LMU Munich, Nussbaumstrasse 7, Munich, Germany. christine.falter@cantab.net.

Funding

Horizon 2020 Framework Programme 824128LMUexcellence 867900-3
6 · The paper itself

Abstract

Reliably diagnosing autism spectrum disorders (ASD) in adulthood poses a challenge to clinicians due to the absence of specific diagnostic markers. This study investigated the potential of interpersonal synchrony (IPS), which has been found to be reduced in ASD, to augment the diagnostic process. IPS was objectively assessed in videos of diagnostic interviews in a representative referral population from two specialized autism outpatient clinics. In contrast to the current screening tools that could not reliably differentiate, we found a significant reduction of IPS in interactions with individuals later diagnosed with ASD (n = 16) as opposed to those not receiving a diagnosis (n = 23). While these findings need to be validated in larger samples, they nevertheless underline the potential of digitally-enhanced diagnostic processes for ASD.

Indexed as

Autism Spectrum DisorderAdultHumansMass ScreeningAutism spectrum disorderDiagnosticsInterpersonal synchronyMotion energy analysisSocial interaction

Identifiers

PMID34331629
PMCPMC9296396

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.