ReviewApplied microbiology and biotechnology2021
Microorganisms: crucial players of smokeless tobacco for several health attributes.
Review in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Microbial architects of cigar fermentation: a critical review of beneficial roles in quality enhancement and detrimental potential for mould spoilage.Archives of microbiology · 2026Review
- The association between periodontal disease and lung cancer: a re-evaluation of independent causal relationships in the presence of smoking as a confounder and an exploration of potential mechanisms.Frontiers in cellular and infection microbiology · 2026Review
- Investigating oral nicotine pouch use among adults in Riyadh, Saudi Arabia: prevalence, awareness, susceptibility, and associated symptoms.Frontiers in public health · 2025Article
- 16S rDNA-Based Amplicon Analysis Unveiled a Correlation Between the Bacterial Diversity and Antibiotic Resistance Genes of Bacteriome of Commercial Smokeless Tobacco Products.Applied biochemistry and biotechnology · 2024Article
- Smokeless Tobacco Harbors Bacteria Involved in Biofilm Formation as Well as Salt and Heavy Metal Tolerance Activity.Applied biochemistry and biotechnology · 2024Article
- Smokeless Tobacco Cessation Support in Dental Hospitals in Pakistan: Dentists and Dental Patients' Perspectives on Current Practices, Support Needed, and Opportunities Available.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Oxygen regulation of microbial communities and chemical compounds in cigar tobacco curing.Frontiers in microbiology · 2024Article
- Effects of fermentation chamber temperature on microbes and quality of cigar wrapper tobacco leaves.Applied microbiology and biotechnology · 2023Article
- Alteration of oral bacteriome of smokeless tobacco users and their association with oral cancer.Applied microbiology and biotechnology · 2023Article
- Altered oral microbiome in Sudanese Toombak smokeless tobacco users carries a newly emerging risk of squamous cell carcinoma development and progression.Scientific reports · 2023Article
- Emerging Oral Nicotine Products and Periodontal Diseases.International journal of dentistry · 2023Review
- Smokeless tobacco consumption induces dysbiosis of oral mycobiome: a pilot study.Applied microbiology and biotechnology · 2022Article
- Delineating the Bacteriome of Packaged and Loose Smokeless Tobacco Products Available in North India.Applied microbiology and biotechnology · 2022Article
- Comparative and analytical characterization of the oral bacteriome of smokeless tobacco users with oral squamous cell carcinoma.Applied microbiology and biotechnology · 2022Article
- Shotgun metagenome sequencing of a Sudanese toombak snuff tobacco: genetic attributes of a high tobacco-specific nitrosamine containing smokeless tobacco product.Letters in applied microbiology · 2022Article
- Characteristics of fungal communities and the sources of mold contamination in mildewed tobacco leaves stored under different climatic conditions.Applied microbiology and biotechnology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Global consumption of smokeless tobacco (SLT) reached 300 million users worldwide majorly from middle-income countries. More than 4000 chemical compounds represent it as one of the noxious consumable products by humans. Besides toxicants/carcinogens, the heavy microbial load on smokeless tobacco further keeps human health at higher risk. Several of these inhabitant microbes participate in biofilm formation and secrete endotoxin/mycotoxins and proinflammatory-like molecules, leading to several oral diseases. Tobacco-associated bacteria exhibit their role in tobacco-specific nitrosamines (TSNAs) formation and acetaldehyde production; both are well-documented carcinogens. Moreover, tobacco exhibits the potential to alter the oral microbiome and induce dysbiotic conditions that lead to the onset of several oral and systemic diseases. Traditional cultivation approaches of microbiology provide partial information of microbial communities of a habitat; therefore, microbiomics has now been employed to study the metagenomes of entire microbial communities. In the past 5 years, few NGS-based investigations have revealed that SLT harbors four dominant phyla (Firmicutes, Proteobacteria, Actinobacteria, and Bacteroidetes) dominating Bacillus spp. and/or Pseudomonas spp. However, functional characterization of their genetic elements will be a more informative attribute to understand the correlation between inhabitant microbial diversity and their relatedness concerning abundance and diseases. This review provides an update on the microbial diversity of SLT and its associated attributes in human health. KEY POINTS: • Heavy microbial load on smokeless tobacco alarms for poor oral hygiene. • Inhabitant microorganisms of SLT participate in TSNA and biofilm formation. • SLTs alter the oral microbiome and causes oral dysbiosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.