Evidence map›Paper›PMID 34331293›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Multiplexed Fourier Transform Infrared and Raman Imaging.

Guillermo Quintás, Bayden R Wood, Hugh J Byrne, David Perez-Guaita

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guillermo QuintásHealth & Biomedicine, LEITAT Technological Center, Barcelona, Spain.
Bayden R WoodFaculty of Science, Centre for Biospectroscopy, School of Chemistry, Monash University, Clayton, VIC, Australia.
Hugh J ByrneFOCAS Research Institute, Technological University Dublin, Dublin, Ireland.
David Perez-GuaitaFOCAS Research Institute, Technological University Dublin, Dublin, Ireland. david.perezguaita@tudublin.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infrared (IR) and Raman spectroscopies are being increasingly employed for the label-free analysis of biochemical samples. Both are vibrational imaging techniques, but they provide complementary information about the chemical composition of the sample, and thus the integration of Raman and IR images leads to a comprehensive understanding of the samples. Here, we summarize the steps needed for performing multiplexed infrared and Raman imaging, identifying and overcoming the two main challenges: first, the technical difficulties caused by the incompatibilities of the techniques and, second, the necessity to extract the information from the large number of vibrational variables found in both IR and Raman spectra.

Indexed as

AnimalsHumansImage Processing, Computer-AssistedImmunohistochemistrySoftwareSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanData fusionInfraredLabel-free imagingMultimodal imagingRaman

Identifiers

PMID34331293

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.