Evidence map›Paper›PMID 34330953›Full record

ArticleScientific reports2021

Compromised dental cells viability following teeth-whitening exposure.

Ola Redha, Morteza Mazinanian, Sabrina Nguyen, Dong Ok Son, Monika Lodyga, Boris Hinz, Marianne Odlyha, Ailbhe McDonald, Laurent Bozec

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ola RedhaDivision of Prosthodontics, UCL Eastman Dental Institute, University College London, 21 University Street, London, WC1E 6DE, UK.ORCID 0000-0003-3039-5237
Morteza MazinanianDivision of Prosthodontics, UCL Eastman Dental Institute, University College London, 21 University Street, London, WC1E 6DE, UK.
Sabrina NguyenFaculty of Dentistry, University of Toronto, 124 Edward Street, Room 459, Toronto, ON, M5G 1G6, Canada.
Dong Ok SonFaculty of Dentistry, University of Toronto, 124 Edward Street, Room 459, Toronto, ON, M5G 1G6, Canada.
Monika LodygaFaculty of Dentistry, University of Toronto, 124 Edward Street, Room 459, Toronto, ON, M5G 1G6, Canada.
Boris HinzFaculty of Dentistry, University of Toronto, 124 Edward Street, Room 459, Toronto, ON, M5G 1G6, Canada.
Marianne OdlyhaDepartment of Biological Sciences, Birkbeck, University of London, Malet Street, London, WC1E 7HX, UK.
Ailbhe McDonaldDivision of Prosthodontics, UCL Eastman Dental Institute, University College London, 21 University Street, London, WC1E 6DE, UK.
Laurent BozecDivision of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, Royal Free Campus, Rowland Hill Street, London, NW3 2PF, UK. l.bozec@utoronto.ca.ORCID 0000-0001-6322-7817
University of Toronto · CAEastman Dental Hospital · GBBirkbeck, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to assess the viability of dental cells following time-dependent carbamide peroxide teeth-whitening treatments using an in-vitro dentin perfusion assay model. 30 teeth were exposed to 5% or 16% CP gel (4 h daily) for 2-weeks. The enamel organic content was measured with thermogravimetry. The time-dependent viability of human dental pulp stem cells (HDPSCs) and gingival fibroblast cells (HGFCs) following either indirect exposure to 3 commercially available concentrations of CP gel using an in-vitro dentin perfusion assay or direct exposure to 5% H

Indexed as

BicuspidCarbamide PeroxideCells, CulturedCell SurvivalDental EnamelDental PulpDentinHumansHydrogen PeroxideMolarTooth Bleaching AgentsCarbamide PeroxideHydrogen PeroxideTooth Bleaching Agents

Identifiers

PMID34330953
PMCPMC8324915
OpenAlexW3183880710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.