SynthesisTranslational psychiatry2021
Genetic association study of childhood aggression across raters, instruments, and age.
Open access · goldAbstract readMeta-Analysis
In one paragraph
Synthesis in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 6 pooled it
9.2field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes.Nature genetics · 2025Pooled it
- Genetics of child aggression, a systematic review.Translational psychiatry · 2024Pooled it
- Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis.Molecular psychiatry · 2022Pooled it
- Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms.Journal of the American Academy of Child and Adolescent Psychiatry · 2022Pooled it
- Continuity of Genetic Risk for Aggressive Behavior Across the Life-Course.Behavior genetics · 2021Pooled it
- DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.Molecular psychiatry · 2021Pooled it
- Genetics of major depressive disorder in a homogeneous population with uniform phenotyping.Molecular psychiatry · 2026Article
- Integrative analysis of single nucleotide polymorphism of PDE7B (rs2327669) with biopsychosocial and biochemical parameters in β-thalassemia major patients in Pakistani Cohort.Molecular biology reports · 2026Article
- Ancient regulatory evolution shapes individual language abilities in present-day humans.Science advances · 2026Article
- A Comparative Study of Moral, Emotional, and Spiritual Intelligence in Parents of Aggressive and Non-Aggressive Children: A Developmental Psychology and Parenting Behavior Perspective.Brain and behavior · 2026Article
- Ancient regulatory evolution shapes individual language abilities in present-day humans.bioRxiv : the preprint server for biology · 2026Article
- Exploring the genetic causality of childhood maltreatment on multiple risk-related outcomes using Mendelian randomization: evidence from European-Ancestry GWAS.European journal of psychotraumatology · 2025Article
- Genetics of Major Depressive Disorder in a Homogeneous Population with Uniform Phenotyping.Research square · 2025Article
- Epilepsy Associated Gene,Genes · 2025Article
- Association between aggression and ADHD polygenic scores and school-age aggression: the mediating role of preschool externalizing behaviors and adverse experiences.European child & adolescent psychiatry · 2025Article
- Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.Molecular psychiatry · 2025Review
- Polygenic overlap of substance use behaviors and disorders with externalizing and internalizing problems independent of genetic correlations.Psychological medicine · 2025Article
- The causal role of male pubertal timing for the development of externalizing and internalizing traits: results from Mendelian randomization studies.Psychological medicine · 2025Article
- Disentangling the effects of self-control and the use of tobacco and cannabis on violence perpetration from childhood to early adulthood.European child & adolescent psychiatry · 2025Article
- Genetic risk for trait aggression and alcohol use predict unique facets of alcohol-related aggression.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
149 authors at 20 institutions in 13 countries.
Hill F IpDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-1991-5019
Camiel M van der LaanDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Eva M L KrapohlInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Isabell BrikellDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Cristina Sánchez-MoraDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0003-4211-1107
Ilja M NolteDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0001-5047-4077
Beate St PourcainMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID 0000-0002-4680-3517
Koen BolhuisDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Teemu PalviainenInstitute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-7847-8384
Hadi ZafarmandDepartment of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Lucía Colodro-CondeQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.ORCID 0000-0002-9004-364X
Scott GordonQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.ORCID 0000-0001-7623-328X
Tetyana ZayatsDepartment of Biomedicine, University of Bergen, Bergen, Norway.
Fazil AlievDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0001-8357-4699
Chang JiangDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
Carol A WangFaculty of Medicine and Health, School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Gretchen SaundersDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
Ville KarhunenDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.ORCID 0000-0001-6064-1588
Anke R HammerschlagDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Daniel E AdkinsDepartment of Sociology, College of Social and Behavioral Science, University of Utah, Salt Lake City, UT, USA.
Richard BorderInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.ORCID 0000-0002-6293-2968
Roseann E PetersonDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Joseph A PrinzCenter for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Elisabeth ThieringInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Ilkka SeppäläDepartment of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Natàlia Vilor-TejedorISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Tarunveer S AhluwaliaCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-7464-3354
Felix R DayMRC Epidemiology Unit, Institute of Metabolic Science, Cambridge Biomedical Campus, University of Cambridge School of Clinical Medicine, Cambridge, UK.ORCID 0000-0003-3789-7651
Jouke-Jan HottengaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-5668-2368
Andrea G AllegriniInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Kaili RimfeldInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0001-5139-065X
Qi ChenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Yi LuDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-9933-3654
Joanna MartinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
María Soler ArtigasDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-3213-1107
Paula RoviraDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Rosa BoschDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-7596-183X
Gemma EspañolDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Josep Antoni Ramos QuirogaDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0003-1622-0350
Alexander NeumannDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID 0000-0001-6653-3203
Judith EnsinkDepartment of Child and Adolescent Psychiatry, Academic Medical Center, Amsterdam, The Netherlands.
Katrina GrasbyQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.ORCID 0000-0001-8539-0228
José J MorosoliQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Xiaoran TongDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
Shelby MarringtonSchool of Public Health, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia.
Christel MiddeldorpDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-6218-0428
James G ScottSchool of Public Health, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia.
Anna VinkhuyzenInstitute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.
Andrey A ShabalinDepartment of Psychiatry, School of Medicine, University of Utah, Salt Lake City, UT, USA.
Robin CorleyInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Luke M EvansInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.ORCID 0000-0002-7458-1720
Karen SugdenCenter for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Silvia AlemanyISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.ORCID 0000-0002-7925-6767
Lærke SassCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-5217-7014
Rebecca VindingCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Kate RuthGenetics of Complex Traits, Royal Devon & Exeter Hospital, University of Exeter Medical School, Exeter, UK.ORCID 0000-0003-4966-9170
Jess TyrrellGenetics of Complex Traits, Royal Devon & Exeter Hospital, University of Exeter Medical School, Exeter, UK.
Gareth E DaviesAvera Institute for Human Genetics, Sioux Falls, SD, USA.
Erik A EhliAvera Institute for Human Genetics, Sioux Falls, SD, USA.ORCID 0000-0002-7865-3015
Fiona A HagenbeekDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-8773-0430
Eveline De ZeeuwDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Toos C E M Van BeijsterveldtDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Harold SniederDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0003-1949-2298
Frank C VerhulstDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Najaf AminDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Alyce M WhippInstitute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland.
Tellervo KorhonenInstitute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland.
Eero VuoksimaaInstitute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland.
Richard J RoseDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA.
André G UitterlindenDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID 0000-0002-7276-3387
Andrew C HeathWashington University, St Louis, MO, USA.
Pamela MaddenWashington University, St Louis, MO, USA.
Jan HaavikDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0001-7865-2808
Jennifer R HarrisDivision of Health Data and Digitalisation, The Norwegian Institute of Public Health, Oslo, Norway.
Øyvind HelgelandDepartment of Genetics and Bioinformatics, Division of Health Data and Digitalization, The Norwegian Institute of Public Health, Bergen, Norway.
Stefan JohanssonDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-2298-7008
Gun Peggy S KnudsenDivision of Health Data and Digitalisation, The Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0002-6193-4291
Pal Rasmus NjolstadDepartment of Clinical Science, University of Bergen, Bergen, Norway.ORCID 0000-0003-0304-6728
Qing LuDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
Alina RodriguezDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.ORCID 0000-0003-1209-8802
Anjali K HendersInstitute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.
Abdullah MamunInstitute for Social Science Research, University of Queensland, Long Pocket, QLD, Australia.
Jackob M NajmanSchool of Public Health, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia.
Sandy BrownDepartment of Psychiatry, University of California, San Diego, CA, USA.ORCID 0000-0001-8780-0323
Christian HopferUniversity of Colorado School of Medicine, Aurora, CO, USA.
Kenneth KrauterDepartment of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO, USA.
Chandra ReynoldsDepartment of Psychology, University of California Riverside, Riverside, CA, USA.
Andrew SmolenInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Michael StallingsInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Sally WadsworthInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
Tamara L WallDepartment of Psychiatry, University of California, San Diego, CA, USA.
Judy L SilbergDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Allison MillerDepartment of Pathology and Biomedical Science, and Carney Centre for Pharmacogenomics, University of Otago Christchurch, Christchurch Central City, New Zealand.ORCID 0000-0003-3816-2251
Liisa Keltikangas-JärvinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-7977-3852
Christian HakulinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Laura Pulkki-RåbackDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Alexandra HavdahlNic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.ORCID 0000-0002-9268-0423
Per MagnusCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Olli T RaitakariCentre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.
John R B PerryMRC Epidemiology Unit, Institute of Metabolic Science, Cambridge Biomedical Campus, University of Cambridge School of Clinical Medicine, Cambridge, UK.ORCID 0000-0001-6483-3771
Sabrina LlopEpidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Valencia, Spain.
Maria-Jose Lopez-EspinosaEpidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Valencia, Spain.
Klaus BønnelykkeCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Hans BisgaardCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Jordi SunyerISGlobal, Barcelona Institute for Global Health, Barcelona, Spain.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-2555-4427
Louise ArseneaultDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.ORCID 0000-0002-2938-2191
Marie StandlInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Joachim HeinrichInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Joseph BodenChristchurch Health and Development Study, Department of Psychological Medicine, University of Otago Christchurch, Christchurch Central City, New Zealand.ORCID 0000-0003-1502-1608
John PearsonBiostatistics and Computational Biology Unit, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch Central City, New Zealand.ORCID 0000-0001-5607-4517
L John HorwoodChristchurch Health and Development Study, Department of Psychological Medicine, University of Otago Christchurch, Christchurch Central City, New Zealand.
Martin KennedyDepartment of Pathology and Biomedical Science, and Carney Centre for Pharmacogenomics, University of Otago Christchurch, Christchurch Central City, New Zealand.ORCID 0000-0002-6445-8526
Richie PoultonDunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-1052-4583
Lindon J EavesDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Hermine H MaesDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
John HewittInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
William E CopelandDepartment of Psychiatry, College of Medicine, University of Vermont, Burlington, VT, USA.ORCID 0000-0002-1348-7781
Elizabeth J CostelloDepartment of Psychiatry, School of Medicine, Duke University, Durham, UK.
Gail M WilliamsSchool of Public Health, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia.
Naomi WrayInstitute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.ORCID 0000-0001-7421-3357
Marjo-Riitta JärvelinDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.ORCID 0000-0002-2149-0630
Matt McGueDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-5580-1433
William IaconoDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
Avshalom CaspiCenter for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Terrie E MoffittCenter for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Andrew WhitehouseTelethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
Craig E PennellFaculty of Medicine and Health, School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.ORCID 0000-0002-0937-6165
Kelly L KlumpDepartment of Psychology, Michigan State University, East Lansing, MI, USA.
S Alexandra BurtDepartment of Psychology, Michigan State University, East Lansing, MI, USA.
Danielle M DickDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0002-1636-893X
Ted Reichborn-KjennerudDepartment of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.
Nicholas G MartinQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.ORCID 0000-0003-4069-8020
Sarah E MedlandQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.ORCID 0000-0003-1382-380X
Tanja VrijkotteDepartment of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Jaakko KaprioInstitute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-3716-2455
Henning TiemeierDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID 0000-0002-4395-1397
George Davey SmithMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID 0000-0002-1407-8314
Catharina A HartmanDepartment of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Albertine J OldehinkelDepartment of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0003-3925-3913
Miquel CasasDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marta RibasésDepartment of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0003-1039-1116
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-3037-5287
Sebastian LundströmGillberg Neuropsychiatry Centre, University of Gothenburg, Gothenburg, Sweden.
Robert PlominInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0002-0756-3629
Meike BartelsDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. m.bartels@vu.nl.ORCID 0000-0002-9667-7555
Michel G NivardDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. m.g.nivard@vu.nl.ORCID 0000-0003-2015-1888
Dorret I BoomsmaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. di.boomsma@vu.nl.ORCID 0000-0002-7099-7972
The University of Queensland · AUUniversity of Colorado Boulder · USUniversity of Helsinki · FIUniversitat Autònoma de Barcelona · ESNorwegian Institute of Public Health · NOQIMR Berghofer Medical Research Institute · AUUniversity of Otago · NZVrije Universiteit Amsterdam · NLDuke University · USKarolinska Institutet · SEUniversity of Copenhagen · DKVirginia Commonwealth University · USKing's College London · GBUniversity Medical Center Groningen · NLAmsterdam UMC Location University of Amsterdam · NLErasmus MC · NLImperial College London · GBUniversitat Pompeu Fabra · ESUniversity of Florida · USUniversity of Minnesota · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MTraining in genetic and neurobehavioral mechanisms of addictionT32DA050560 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Scott Ian Vrieze · 2020 to 2026
$2.0MMedical Research Council G1002190Medical Research Council MC_UU_00006/2Medical Research Council MC_UU_00011/1Medical Research Council MC_UU_12015/2NCATS NIH HHS UL1 TR001863NIDA NIH HHS T32 DA050560
Abstract
Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. We analyzed phenotype assessments for a total of 328 935 observations from 87 485 children aged between 1.5 and 18 years, while accounting for sample overlap. We also meta-analyzed within subsets of the data, i.e., within rater, instrument and age. SNP-heritability for the overall meta-analysis (AGG
Indexed as
AggressionMental DisordersAdolescentChildChild, PreschoolFemaleGenetic Association StudiesGenome-Wide Association StudyHumansInfantRetrospective Studies
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.