Evidence map›Paper›PMID 34330880›Full record

Observational studyBMJ quality & safety2023

Days alive and at home after hip fracture: a cross-sectional validation of a patient-centred outcome measure using routinely collected data.

Daniel I McIsaac, Robert Talarico, Angela Jerath, Duminda N Wijeysundera

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in BMJ quality & safety, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 31 citations in OpenAlex.

  1. Valid Standard Errors for Bayesian Quantile Regression With Clustered and Independent Data.Journal of educational and behavioral statistics : a quarterly publication sponsored by the American Educational Research Association and the American Statistical Association · 2026
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  2. Patterns of patient worry following major emergency abdominal surgery: a 180-day follow-up study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
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  7. A novel patient-centered outcome in cancer care, days at home: a scoping review and guide for its future use.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  15. Association Between Surgeon Sex and Days Alive at Home Following Surgery: A Population-Based Cohort Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Daniel I McIsaacAnesthesiology and Pain Medicine, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada dmcisaac@toh.on.ca.ORCID 0000-0002-8543-1859
Robert TalaricoInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Angela JerathAnesthesia, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
Duminda N WijeysunderaAnesthesia, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.ORCID 0000-0002-5897-8605
Ottawa Hospital · CASt. Michael's Hospital · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

CIHR PJT-165805
6 · The paper itself

Abstract

backgroundDays alive and at home (DAH) is a patient centered outcome measureable in routinely collected health data. The validity and minimally important difference (MID) in hip fracture have not been evaluated.

objectiveWe assessed construct and predictive validity and estimated a MID for the patient-centred outcome of DAH after hip fracture admission.

methodsThis is a cross-sectional observational study using linked health administrative data in Ontario, Canada. DAH was calculated as the number of days alive within 90 days of admission minus the number of days hospitalised or institutionalised. All hospital admissions (2012-2018) for hip fracture in adults aged >50 years were included. Construct validity analyses used Bayesian quantile regression to estimate the associations of postulated patient, admission and process-related variables with DAH. The predictive validity assessed was the correlation of DAH in 90 days with the value from 91 to 365 days; and the association and discrimination of DAH in 90 days predicting subsequent mortality. MID was estimated by averaging distribution-based and clinical anchor-based estimates.

resultsWe identified 63 778 patients with hip fracture. The median number of DAH was 43 (range 0-87). In the 90 days after admission, 8050 (12.6%) people died; a further 6366 (10.0%) died from days 91 to 365. Associations between patient-level and admission-level factors with the median DAH (lower with greater age, frailty and comorbidity, lower if admitted to intensive care or having had a complication) supported construct validity. DAH in 90 days after admission was strongly correlated with DAH in 365 days after admission (r=0.922). An 11-day MID was estimated.

conclusionDAH has face, construct and predictive validity as a patient-centred outcome in patients with hip fracture, with an estimated MID of 11 days. Future research is required to include direct patient perspectives in confirming MID.

Indexed as

Hip FracturesRoutinely Collected Health DataAdultBayes TheoremCross-Sectional StudiesHumansOntarioOutcome Assessment, Health Carecomparative effectiveness researchevaluation methodologyhealth services researchpatient-centred caresurgery

Identifiers

PMID34330880
PMCPMC10447366
OpenAlexW3184882844

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.