ArticleProceedings of the National Academy of Sciences of the United States of America2021
Morphogenesis and cell ordering in confined bacterial biofilms.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- Granular Hydrogel Composites as Matrices for Engineered Living Materials.ACS applied polymer materials · 2026Article
- Biosurfactants direct the evolutionary dynamics of surface-associated microbial systems.Science advances · 2026Article
- Physical encounters impose a consistency-amount trade-off on bacterial group formation in marine environments.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Deep learning-based high-information-content graph representation of early stage bacterial biofilms.NPJ biofilms and microbiomes · 2026Article
- Emergent spatial structure in the gut microbiota is driven by bacterial growth and gut contractions.PLoS biology · 2026Article
- Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Elasticity promotes directional transport ofSoft matter · 2026Article
- Spatial proximity dictates bacterial competition and expansion in microbial communities.Nature communications · 2025Article
- Understanding the development of bacterial colony: Physiology, new technology, and modeling.Quantitative biology (Beijing, China) · 2025Review
- Stress-hardening behaviour of biofilm streamers.Nature communications · 2025Article
- Controlled Release of Microorganisms from Engineered Living Materials.ACS applied materials & interfaces · 2025Article
- Dissecting the physics of bacterial biofilms with agent-based simulations.Current opinion in solid state & materials science · 2025Article
- Spatiotemporal development of expanding bacterial colonies driven by emergent mechanical constraints and nutrient gradients.Nature communications · 2025Article
- Bacterial Species in Engineered Living Materials: Strategies and Future Directions.Microbial biotechnology · 2025Review
- Harnessing traditional medicine: A dual-action antimicrobial combination against pathogens.iScience · 2025Article
- Article
- Growth of nonmotile stress-responsive bacteria in 3D colonies under confining pressure.Biophysical journal · 2025Article
- On the prospects of basal cognition research becoming fully evolutionary: promising avenues and cautionary notes.History and philosophy of the life sciences · 2025Article
- Novel ellipsoid-like granules exhibit enhanced anammox performance compared to sphere-like granules.Water research X · 2024Article
- The biophysical basis of bacterial colony growth.Nature physics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms are aggregates of bacterial cells surrounded by an extracellular matrix. Much progress has been made in studying biofilm growth on solid substrates; however, little is known about the biophysical mechanisms underlying biofilm development in three-dimensional confined environments in which the biofilm-dwelling cells must push against and even damage the surrounding environment to proliferate. Here, combining single-cell imaging, mutagenesis, and rheological measurement, we reveal the key morphogenesis steps of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.