ReviewMolecular pharmacology2022
The Tails of Protein Kinase A.
Open access · bronzeAbstract readReview
In one paragraph
Review in Molecular pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 44 citations in OpenAlex.
- Mussel Spermatozoa Express a Specific Isoform of the Catalytic Subunit of cAMP-Dependent Protein Kinase.Molecular reproduction and development · 2026Article
- Centrosome-Signaling Pathway Crosstalk: A Core Hub From Cellular Homeostasis to Disease.Cytoskeleton (Hoboken, N.J.) · 2026Review
- Identification of the Potential Functions of theInternational journal of molecular sciences · 2026Article
- The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region.Life science alliance · 2026Article
- Cyclin-E/A/CDK1/2 Kinetic Landscapes Drive Cell Cycle Phase-Specific Progression and Guide Cyclin-E Degradation Strategy.Journal of chemical information and modeling · 2026Article
- The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.Nature communications · 2026Article
- Beyond the mutations: spatiotemporal regulation of CFTR by cAMP and calcium signaling in epithelial physiology and cystic fibrosis.Cellular & molecular biology letters · 2025Review
- Structural insights and biophysical characterization of p90RSK2:ERK2 complex.The Biochemical journal · 2025Article
- The beta1-adrenergic receptor in the heart.Cell death discovery · 2025Review
- Biochemical characterization of the full-length isoform of soluble adenylyl cyclase.The Journal of biological chemistry · 2025Article
- Crustacean Protein Kinases A and C: Bioinformatic Characterization in Decapods and Other Non-Model Organisms.International journal of molecular sciences · 2025Article
- Distinct Allosteric Networks in CDK4 and CDK6 in the Cell Cycle and in Drug Resistance.Journal of molecular biology · 2025Article
- Review
- Redox Regulation of cAMP-Dependent Protein Kinase and Its Role in Health and Disease.Life (Basel, Switzerland) · 2025Review
- Article
- Biochemical pharmacology of adenylyl cyclases in cancer.Biochemical pharmacology · 2024Review
- Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-protein interactions.Cellular and molecular life sciences : CMLS · 2024Article
- Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2.eLife · 2024Article
- Role of the leucine-rich repeat protein kinase 2 C-terminal tail in domain cross-talk.The Biochemical journal · 2024Article
- Targeting phosphorylation circuits on CREB and CRTCs as the strategy to prevent acquired skin hyperpigmentation.International journal of biological sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Susan S TaylorDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.) staylor@ucsd.edu.
Kristoffer SøbergDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.).
Evan KoboriDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.).
Jian WuDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.).
Sabine PautzDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.).
Friedrich W HerbergDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.).
Bjørn Steen SkålheggDepartments of Pharmacology (S.S.T.) and Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (S.S.T., E.K., J.W.); Department of Medical Genetics, Oslo University Hospital, Oslo, Norway (K.S.); Department of Biochemistry, University of Kassel, Kassel, Germany (S.P., F.W.H.); and Division for Molecular Nutrition, University of Oslo, Norway (B.S.S.).
University of California, San Diego · USUniversity of Kassel · DEOslo University Hospital · NOUniversity of Oslo · NO
Funding
Lessons Learned from PKA: Assembly of Dynamic Macromolecular SwitchesR35GM130389 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUSAN S. TAYLOR · 2019 to 2026
$5.7MIlluminating the Role of understudied PRKACB Splice Variants in PKA SignalingR03TR002947 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAYLOR, SUSAN S. · 2019 to 2019
$158kNCATS NIH HHS R03 TR002947NIGMS NIH HHS R35 GM130389
Abstract
Protein kinase A (PKA) is a holoenzyme consisting of a regulatory (R)-subunit dimer and two catalytic (C)-subunits. There are two major families of C-subunits, C
Indexed as
Cyclic AMP-Dependent Protein KinasesProtein KinasesAnimalsCyclic AMP-Dependent Protein Kinase RIalpha SubunitHumansProtein IsoformsSignal TransductionCyclic AMP-Dependent Protein Kinase RIalpha SubunitCyclic AMP-Dependent Protein KinasesProtein IsoformsProtein Kinases
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.