Evidence map›Paper›PMID 34330754›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2021

Postnatal Ozone Exposure Disrupts Alveolar Development, Exaggerates Mucoinflammatory Responses, and Suppresses Bacterial Clearance in Developing

Ishita Choudhary, Thao Vo, Kshitiz Paudel, Radha Yadav, Yun Mao, Sonika Patial, Yogesh Saini

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Single-cell transcriptomics reveal alveolar macrophage-specific responses in single-hit ozone exposure model in mice.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Case report:Frontiers in immunology · 2022
    Article
  10. Induction of whole-body gene deletionFrontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ishita ChoudharyDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.ORCID 0000-0001-8242-3928
Thao VoDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.
Kshitiz PaudelDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.ORCID 0000-0001-7125-8381
Radha YadavDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.
Yun MaoDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.ORCID 0000-0003-2768-6308
Sonika PatialDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.
Yogesh SainiDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA ysaini@lsu.edu.ORCID 0000-0002-8324-2122
Louisiana State University · US

Funding

The role of adipocyte-driven inflammation and leptin pathway in pulmonary viral infections caused by SARS-CoV-2 and influenza A virusesP20GM130555 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Stephania A Cormier, TAMMY R DUGAS · 2019 to 2026
$19.9M
Understanding the role of myeloid cells in ozone-induced airway diseaseR01ES030125 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAINI, YOGESH · 2019 to 2024
$2.7M
NIEHS NIH HHS R01 ES030125NIGMS NIH HHS P20 GM130555
6 · The paper itself

Abstract

Increased levels of ambient ozone, one of the six criteria air pollutants, result in respiratory tract injury and worsening of ongoing lung diseases. However, the effect of ozone exposure on the respiratory tract undergoing active lung development and simultaneously experiencing mucoinflammatory lung diseases, such as cystic fibrosis, remains unclear. To address these questions, we exposed

Indexed as

AnimalsBacteriaCystic FibrosisDisease Models, AnimalEpithelial Sodium ChannelsInflammationLungMacrophagesMiceMice, TransgenicMucusOzonePostnatal CareEpithelial Sodium ChannelsOzoneScnn1b protein, mouse

Identifiers

PMID34330754
PMCPMC8654340
OpenAlexW3184189093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.