Evidence map›Paper›PMID 34330515›Full record

ReviewClinical nutrition ESPEN2021

Nutrition guidelines for critically ill adults admitted with COVID-19: Is there consensus?

Lee-Anne S Chapple, Oana A Tatucu-Babet, Kate J Lambell, Kate Fetterplace, Emma J Ridley

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical nutrition ESPEN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Comparison of the NUTRIC, NUTRICm and NUTRICpcr scores in critically ill patients ventilated for COVID-19.Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025
    Observational
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Review
  9. COVID, the Gut, and Nutritional Implications.Current surgery reports · 2023
    Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lee-Anne S ChappleCentre of Research Excellence in Nutritional Physiology, The University of Adelaide, North Terrace, Adelaide, 5000, South Australia, Australia; Intensive Care Research, Royal Adelaide Hospital, Port Road, Adelaide, 5000, South Australia, Australia. Electronic address: lee.anne.chapple@adelaide.edu.au.
Oana A Tatucu-BabetAustralian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.
Kate J LambellAustralian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia; Nutrition Department, Alfred Health, Melbourne, Victoria, Australia.
Kate FetterplaceAllied Health Department (Clinical Nutrition), Royal Melbourne Hospital, Melbourne, Victoria, Australia; The University of Melbourne, Melbourne Medical School, Department of Medicine and Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Emma J RidleyAustralian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia; Nutrition Department, Alfred Health, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Coronavirus Disease 2019 (COVID-19) pandemic has overwhelmed hospital systems globally, resulting in less experienced staff caring for critically ill patients within the intensive care unit (ICU). Many guidelines have been developed to guide nutrition care.

aimTo identify key guidelines or practice recommendations for nutrition support practices in critically ill adults admitted with COVID-19, to describe similarities and differences between recommendations, and to discuss implications for clinical practice.

methodsA literature review was conducted to identify guidelines affiliated with or endorsed by international nutrition societies or dietetic associations which included recommendations for the nutritional management of critically ill adult patients with COVID-19. Data were extracted on pre-defined key aspects of nutritional care including nutrition prescription, delivery, monitoring and workforce recommendations, and key similarities and discrepancies, as well as implications for clinical practice were summarized.

resultsTen clinical practice guidelines were identified. Similar recommendations included: the use of high protein, volume restricted enteral formula delivered gastrically and commenced early in ICU and introduced gradually, while taking into consideration non-nutritional calories to avoid overfeeding. Specific advice for patients in the prone position was common, and non-intubated patients were highlighted as a population at high nutritional risk. Major discrepancies included the use of indirect calorimetry to guide energy targets and advice around using gastric residual volumes (GRVs) to monitor feeding tolerance.

conclusionOverall, common recommendations around formula type and route of feeding exist, with major discrepancies being around the use of indirect calorimetry and GRVs, which reflect international ICU nutrition guidelines.

Indexed as

Nutritional RequirementsNutrition PolicyConsensusCOVID-19Critical CareCritical IllnessHumansMalnutritionNutritional StatusSARS-CoV-2COVID-19DietitianEnteral nutritionGuidelineNutrition supportRecommendations

Identifiers

PMID34330515
PMCPMC8146268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.