Evidence map›Paper›PMID 34330265›Full record

ArticleBMC medical informatics and decision making2021

Learning rich features with hybrid loss for brain tumor segmentation.

Daobin Huang, Minghui Wang, Ling Zhang, Haichun Li, Minquan Ye, Ao Li

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daobin HuangSchool of Information Science and Technology, and Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, 230027, China.
Minghui WangSchool of Information Science and Technology, and Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, 230027, China.
Ling ZhangDepartment of Biochemistry, Wannan Medical College, Wuhu, 241002, China.
Haichun LiSchool of Information Science and Technology, and Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, 230027, China.
Minquan YeSchool of Information Science and Technology, and Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, 230027, China. ymq@wnmc.edu.cn.
Ao LiSchool of Information Science and Technology, and Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, 230027, China. aoli@ustc.edu.cn.ORCID 0000-0001-9910-8967
University of Science and Technology of China · CNWannan Medical College · CN

Funding

the Anhui Provincial Natural Science Foundation of China 1508085QH185the Anhui Provincial Natural Science Foundation of China 1708085MF142the National Natural Science Foundation of China 61471331the National Natural Science Foundation of China 61672386the National Natural Science Foundation of China 61871361the National Natural Science Foundation of China 61971393
6 · The paper itself

Abstract

backgroundAccurately segment the tumor region of MRI images is important for brain tumor diagnosis and radiotherapy planning. At present, manual segmentation is wildly adopted in clinical and there is a strong need for an automatic and objective system to alleviate the workload of radiologists.

methodsWe propose a parallel multi-scale feature fusing architecture to generate rich feature representation for accurate brain tumor segmentation. It comprises two parts: (1) Feature Extraction Network (FEN) for brain tumor feature extraction at different levels and (2) Multi-scale Feature Fusing Network (MSFFN) for merge all different scale features in a parallel manner. In addition, we use two hybrid loss functions to optimize the proposed network for the class imbalance issue.

resultsWe validate our method on BRATS 2015, with 0.86, 0.73 and 0.61 in Dice for the three tumor regions (complete, core and enhancing), and the model parameter size is only 6.3 MB. Without any post-processing operations, our method still outperforms published state-of-the-arts methods on the segmentation results of complete tumor regions and obtains competitive performance in another two regions.

conclusionsThe proposed parallel structure can effectively fuse multi-level features to generate rich feature representation for high-resolution results. Moreover, the hybrid loss functions can alleviate the class imbalance issue and guide the training process. The proposed method can be used in other medical segmentation tasks.

Indexed as

Brain NeoplasmsImage Processing, Computer-AssistedBrainHumansMagnetic Resonance ImagingNeural Networks, ComputerBrain tumor segmentationClass imbalanceDeep learningRich feature representation

Identifiers

PMID34330265
PMCPMC8323198
OpenAlexW3186270916

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.