Evidence map›Paper›PMID 34329597›Full record

ArticleStem cell reports2021

Inclusivity and diversity: Integrating international perspectives on stem cell challenges and potential.

Robin Fears, Hidenori Akutsu, Lara Theresa Alentajan-Aleta, Andrés Caicedo, Antonio Carlos Campos de Carvalho, Miodrag Čolić, Jillian Cornish, Giulio Cossu, Patrice Debré, Geoffrey Dierckxsens and 11 more

Abstract read
In one paragraph

Article in Stem cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Early-Phase Clinical Trials of Bio-Artificial Organ Technology: A Systematic Review of Ethical Issues.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Pooled it
  3. Article
  4. Article
  5. Review
  6. The Art of Stem Cell-Based Therapy.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Robin FearsInterAcademy Partnership, ICTP Campus, c/o TWAS, Trieste 34151, Italy. Electronic address: robin.fears@easac.eu.
Hidenori AkutsuCenter for Regenerative Medicine, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Lara Theresa Alentajan-AletaDepartment of Internal Medicine, University of the Philippines, Manila, Philippines.
Andrés CaicedoEscuela de Medicina, Universidad San Francisco de Quito, USFQ, Quito, Ecuador.
Antonio Carlos Campos de CarvalhoInstituto de Biofisica Carlos Chagas Filho, Universidade Federal, Rio de Janeiro Rj21941-902, Brazil.
Miodrag ČolićDepartment of Medical Sciences, Serbian Academy of Sciences and Arts, Belgrade, Serbia.
Jillian CornishDepartment of Medicine, University of Auckland, Auckland 1142, New Zealand.
Giulio CossuDivision of Cell Matrix Biology and Regenerative Medicine, University of Manchester, Manchester M13 9PL, UK.
Patrice DebréDepartement d'immunologie, Hopital Pitie Salpetriere, 75013 Paris, France.
Geoffrey DierckxsensInstitute of Philosophy of the Czech Academy of Sciences, 110 00 Prague 1, Czech Republic.
Nagwa El-BadriCenter of Excellence for Stem Cells and Regenerative Medicine, Zewail City of Science and Technology, 12578 Giza, Egypt.
George GriffinInstitute for Infection and Immunity, St. George's, University of London, London SW17 ORE, UK.
Patrick Chingo-Ho HsiehInstitute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
Maneesha S InamdarMolecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.
Pradeep KumarWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, University of the Witwatersrand, Johannesburg 2193, South Africa.
Consuelo Macias AbrahamInstitute of Haematology and Immunology, "Dr C. Jose Manuel Ballester Santovenia", Havana 10400, Cuba.
Romaldas MaciulaitisInstitute of Physiology and Pharmacology, Medical Faculty of the Lithuanian University of Health Sciences, 49264 Kaunas, Lithuania.
Mamun Al MahtabDepartment of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka 1000, Bangladesh.
Fergal J O'BrienTissue Engineering Research Group, Department of Anatomy & Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Michael Sean PepperInstitute for Cellular and Molecular Medicine, Department of Immunology, and South African Medical Research Council Extramural Unit for Stem Cell Research and Therapy, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Volker Ter MeulenInterAcademy Partnership, ICTP Campus, c/o TWAS, Trieste 34151, Italy.

Funding

Medical Research Council MR/S015116/1
6 · The paper itself

Abstract

Regenerative medicine has great potential. The pace of scientific advance is exciting and the medical opportunities for regeneration and repair may be transformative. However, concerns continue to grow, relating to problems caused both by unscrupulous private clinics offering unregulated therapies based on little or no evidence and by premature regulatory approval on the basis of insufficient scientific rationale and clinical evidence. An initiative by the InterAcademy Partnership convened experts worldwide to identify opportunities and challenges, with a focus on stem cells. This was designed to be inclusive and consensus outputs reflected the diversity of the global research population. Among issues addressed for supporting research and innovation while protecting patients were ethical assessment; pre-clinical and clinical research; regulatory authorization and medicines access; and engagement with patients, policy makers, and the public. The InterAcademy Partnership (IAP) identified options for action for sharing good practice and building collaboration within the scientific community and with other stakeholders worldwide.

Indexed as

Research DesignAnimalsBiomedical ResearchCell- and Tissue-Based TherapyHumansInformation DisseminationInternationalityRegenerative MedicineStem Cellsbiomedical policyglobalregenerative medicinestem cells

Identifiers

PMID34329597
PMCPMC8365097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.