ArticleStem cell reports2021
Patients' perspectives on the derivation and use of organoids.
Article in Stem cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- The role of gastric cancer patient-derived organoids in precision medicine: Clinicians' perspective.Stem cell reports · 2026Article
- Ethics and Regulation of Human Brain Organoid Research: Recommendations from the Asia Pacific Neuroethics Working Group.Asian bioethics review · 2026Article
- Japanese attitudes toward human brain organoid research: broad support amid ethical concerns.Frontiers in genetics · 2026Article
- From Cells to Organoids: Approaches, Regulatory Mechanisms, Applications, and Challenges of Organoids.Cells · 2025Review
- The ethical aspects of human organ-on-chip models: A mapping review.Stem cell reports · 2025Review
- The ethics and economics of organoid commercialization: potential donors' perspectives.BMC medical ethics · 2025Article
- Research progress and application status of organoid in breast cancer subtypes.Biomolecules & biomedicine · 2025Review
- Biomedical applications of organoids in genetic diseases.Medical review (2021) · 2025Review
- Japanese attitudes toward cell donation in human brain organoid research: many oppose broad consent.Frontiers in genetics · 2025Article
- Moral Intuition Regarding the Possibility of Conscious Human Brain Organoids: An Experimental Ethics Study.Science and engineering ethics · 2024Article
- Human Brain Organoid Research and Applications: Where and How to Meet Legal Challenges?Journal of bioethical inquiry · 2024Review
- The Ethics of Stem Cell-Based Embryo-Like Structures : A Focus Group Study on the Perspectives of Dutch Professionals and Lay Citizens.Journal of bioethical inquiry · 2024Article
- Anticipating in vitro gametogenesis: Hopes and concerns for IVG among diverse stakeholders.Stem cell reports · 2024Article
- Cardiac organoids do not warrant additional moral scrutiny.BMC medical ethics · 2024Article
- The ethical and legal challenges of human foetal brain tissue-derived organoids : At the intersection of science, ethics, and regulation.EMBO reports · 2024Article
- The Donation of Human Biological Material for Brain Organoid Research: The Problems of Consciousness and Consent.Science and engineering ethics · 2024Article
- The importance of accurate representation of human brain organoid research.Trends in biotechnology · 2023Article
- Donor perspectives on informed consent and use of biospecimens for brain organoid research.Stem cell reports · 2023Article
- Public perceptions and expectations: Disentangling the hope and hype of organoid research.Stem cell reports · 2023Article
- Human cerebral organoids: the ethical stance of scientists.Stem cell research & therapy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Organoid research is enhancing understanding of human development and diseases as well as aiding in medication development and selection, raising hopes for even more future therapeutic options. Nevertheless, this work raises important ethical issues and there is a paucity of data regarding patients' perspectives on them. We report on 60 interviews with adult patients or parents of pediatric patients from diverse disease populations who receive medical care at a major academic research institution in the United States. Interviewees expressed broad support for organoid development and use. However, patients viewed brain organoids, and sometimes gonadal organoids, as morally distinct; and some organoid research poses moral concerns. Nonetheless, patients generally understood the potential value of such research and approved of it, provided it was aimed at good intent and conducted with ethical oversight and a robust consent process. These data should help inform conceptual and policy deliberations about appropriate organoid use.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.