ArticleUnited European gastroenterology journal2021
Epidemiology of pyogenic liver abscesses in Germany: Analysis of incidence, risk factors and mortality rate based on routine data from statutory health insurance.
Article in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 37 citations in OpenAlex.
- Clinical efficacy of ulinastatin in the treatment of unliquefied pyogenic liver abscess complicated by septic shock: A randomized controlled trial.Immunity, inflammation and disease · 2023Trial
- When Clinical Improvement Does Not Reflect Radiological Response: A Culture-Negative Giant Pyogenic Liver Abscess.Healthcare (Basel, Switzerland) · 2026Article
- Integration of the National Early Warning Score 2 and the procalcitonin-to-albumin ratio for sepsis prediction in patients with pyogenic liver abscess: a retrospective cohort study.BMC infectious diseases · 2026Article
- Comparison of Clinical Features and Treatment Outcomes of Pyogenic Liver Abscess in Diabetic and Non-Diabetic Patients in a Chinese Hospital.Infection and drug resistance · 2026Article
- Pyogenic liver abscess in the North Denmark Region - a population-based cohort study (2010-2022).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Clinical characteristics and outcomes of liver abscesses: a 12-year retrospective analysis from a tertiary care center in the United Arab Emirates.Frontiers in medicine · 2025Article
- Pyogenic liver abscess and sepsis caused by mixed anaerobic bacteria in an immunocompetent adult: a case report.Frontiers in medicine · 2025Article
- Incidence, Risk Factors, and Subsequent Health Outcomes of Pyogenic Liver Abscesses: A Scoping Review of Evidence From Population-Based Studies.Gastroenterology research and practice · 2025Review
- Liver abscess caused byAmerican journal of translational research · 2025Article
- Clinical management, pathogen spectrum and outcomes in patients with pyogenic liver abscess in a German tertiary-care hospital.Scientific reports · 2024Observational
- Pyogenic liver abscess after Milligan-Morgan hemorrhoidectomy.Journal of surgical case reports · 2024Article
- Clinical characteristics, effectiveness and cost of different treatment methods for invasiveZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Case report: Brain infarction following percutaneous drainage of a liver abscess post-chemotherapy for pancreatic head cancer.Frontiers in medicine · 2024Article
- A Validation Study of the Danish ICD-10 Diagnosis Code K75.0 for Pyogenic Liver Abscess.Clinical epidemiology · 2024Article
- Article
- Pyogenic liver abscess associated withHeliyon · 2023Article
- Recurrent Liver Abscess in a Non-toxic Patient.Cureus · 2023Article
- Review
- Evaluation of the Diagnostic Performance of mNGS in Detecting Intra-Abdominal Infections of the Emergency Department Patients.Infection and drug resistance · 2023Article
- A rare Danish case ofClinical case reports · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPyogenic liver abscesses (PLAs) represent potentially life-threatening abdominal conditions that require immediate diagnosis and therapy. European and American incidence figures vary between one and 15 per 100,000 per year. Structured epidemiological data for European countries are not available.
objectiveTo systematically characterize the epidemiology and clinical outcome of PLA in Germany.
methodsIn representative statutory health insurance data from four million people in 2013-2019, the prevalence and incidence with clinical coding of International Statistical Classification of Diseases and Related Health Problems (ICD)-10 code K75.0 were selected (n = 1118). Furthermore, demographics, relevant comorbidities, hospitalizations, mortality and complications were determined within one year.
resultsThe incidence of PLA was approximately seven per 100,000. The average age at diagnosis was 66 years; 65% were male. Of these, biliary disease was documented in over 60% and infectious intestinal diseases were found in 21% within the same or previous calendar year. PLA patients had high comorbidity indices. Liver transplant status, malignancies of the liver and biliary system, liver cirrhosis and pancreatitis were strongly associated. Intensive care was documented in 27% of PLA cases. Nine percent died within 12 months, most with an underlying malignant disease.
conclusionPyogenic liver abscess is a rare disease with high morbidity. Predisposing and risk factors include intestinal and biliary diseases as well as hepatic malignancies. Further research should focus on PLA therapy within prospective surveys and controlled clinical trials.
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