Evidence map›Paper›PMID 34329305›Full record

ArticlePLoS neglected tropical diseases2021

Social determinants associated with Zika virus infection in pregnant women.

Nivison Nery, Juan P Aguilar Ticona, Claudia Gambrah, Simon Doss-Gollin, Adeolu Aromolaran, Valmir Rastely-Júnior, Millani Lessa, Gielson A Sacramento, Jaqueline S Cruz, Daiana de Oliveira and 18 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 6 institutions in 2 countries.

Nivison NeryInstituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil.ORCID 0000-0002-8164-0602
Juan P Aguilar TiconaInstituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil.
Claudia GambrahDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America.ORCID 0000-0002-2448-2265
Simon Doss-GollinPrecision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, United States of America.ORCID 0000-0001-8797-7452
Adeolu AromolaranDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America.
Valmir Rastely-JúniorFaculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, BA-Brazil.ORCID 0000-0001-8350-6995
Millani LessaInstituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil.ORCID 0000-0002-3535-6926
Gielson A SacramentoInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.
Jaqueline S CruzInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.
Daiana de OliveiraInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.
Laiara Lopes Dos SantosInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.ORCID 0000-0002-8707-7005
Crislaine G da SilvaInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.
Viviane F BotossoDevelopment and Innovation Center, Laboratory of Virology, Butantan Institute, São Paulo, Brazil.
Camila P SoaresDepartamento de Microbiologia. Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-2161-7179
Danielle Bastos AraujoDepartamento de Microbiologia. Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Danielle B OliveiraDevelopment and Innovation Center, Laboratory of Virology, Butantan Institute, São Paulo, Brazil.
Rubens Prince Dos Santos AlvesLaboratório de Desenvolvimento de Vacinas, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0001-5538-6025
Robert Andreata-SantosLaboratório de Desenvolvimento de Vacinas, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-4506-3756
Edison L DurigonDevelopment and Innovation Center, Laboratory of Virology, Butantan Institute, São Paulo, Brazil.
Luís Carlos de Souza FerreiraLaboratório de Desenvolvimento de Vacinas, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Elsio A WunderInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.ORCID 0000-0002-5239-8511
Ricardo KhouriInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.ORCID 0000-0001-5664-4436
Jamary Oliveira-FilhoFaculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, BA-Brazil.
Isadora C de SiqueiraInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.ORCID 0000-0002-2520-4099
Antônio R P AlmeidaFaculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, BA-Brazil.
Mitermayer G ReisInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.
Albert I KoInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil.
Federico CostaInstituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil.
Universidade Federal da Bahia · BRMinistério da Saúde · BRUniversidade de São Paulo · BRYale University · USInstituto Butantan · BRBoston Children's Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Naturally-Acquired and Vaccine-Mediated Immunity to LeptospirosisR01AI121207 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG, REIS, MITERMAYER GALVAO DOS · 2016 to 2020
$6.4M
Short-Term Reserch Training: Students in Health SchoolsT35HL007649 · NHLBI · YALE UNIVERSITY · PI Sarwat I Chaudhry, Erica L Herzog · 1987 to 2026
$5.7M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
Disease Determinants of Urban LeptospirosisU01AI088752 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG · 2010 to 2014
$3.6M
Natural History of Urban LeptospirosisR01AI052473 · NIAID · YALE UNIVERSITY · PI KO, ALBERT ICKSANG · 2003 to 2013
$2.8M
Ecoepidemiology of leptospirosis in the urban slums of BrazilR01TW009504 · FIC · YALE UNIVERSITY · PI BEGON, MICHAEL, CHILDS, JAMES EMORY · 2012 to 2016
$2.2M
Rodent Population Dynamics and Leptospirosis Infection in Urban Slum EnviornmentsF31AI114245 · NIAID · YALE UNIVERSITY · PI HACKER, KATHRYN PATRICIA · 2014 to 2015
$55k
FIC NIH HHS D43 TW010540FIC NIH HHS R01 TW009504FIC NIH HHS R25 TW009338NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T35 HL007649NIAID NIH HHS F31 AI114245NIAID NIH HHS R01 AI052473NIAID NIH HHS R01 AI121207NIAID NIH HHS U01 AI088752Wellcome TrustWellcome Trust 102330/Z/13/ZWellcome Trust 218987/Z/19/Z
6 · The paper itself

Abstract

This study aims to describe the sociodemographic determinants associated with exposure to Zika Virus (ZIKV) in pregnant women during the 2015-2016 epidemic in Salvador, Brazil.

methodsWe recruited women who gave birth between October 2015 and January 2016 to a cross-sectional study at a referral maternity hospital in Salvador, Brazil. We collected information on their demographic, socioeconomic, and clinical characteristics, and evaluated their ZIKV exposure using a plaque reduction neutralization test. Logistic regression was then used to assess the relationship between these social determinants and ZIKV exposure status.

resultsWe included 469 pregnant women, of whom 61% had a positive ZIKV result. Multivariate analysis found that lower education (adjusted Prevalence Rate [aPR] 1.21; 95%CI 1.04-1.35) and food insecurity (aPR 1.17; 95%CI 1.01-1.30) were positively associated with ZIKV exposure. Additionally, age was negatively associated with the infection risk (aPR 0.99; 95%CI 0.97-0.998).

conclusionEve after controlling for age, differences in key social determinants, as education and food security, were associated with the risk of ZIKV infection among pregnant women in Brazil. Our findings elucidate risk factors that can be targeted by future interventions to reduce the impact of ZIKV infection in this vulnerable population.

Indexed as

Socioeconomic FactorsAdultBrazilCross-Sectional StudiesFemaleHumansPregnancyPregnancy Complications, InfectiousRisk FactorsZika Virus Infection

Identifiers

PMID34329305
PMCPMC8323902
OpenAlexW3187020367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.