Evidence map›Paper›PMID 34328806›Full record

ArticleDrug delivery2021

Formulation, characterization, and cellular toxicity assessment of tamoxifen-loaded silk fibroin nanoparticles in breast cancer.

Afrasim Moin, Shahid Ud Din Wani, Riyaz Ali Osmani, Amr S Abu Lila, El-Sayed Khafagy, Hany H Arab, Hosahalli V Gangadharappa, Ahmed N Allam

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Biomimetic FeCurrent pharmaceutical biotechnology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Formulation optimization,Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Anti-Tumor Potential ofAntioxidants (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Afrasim MoinDepartment of Pharmaceutics, College of Pharmacy, University of Hail, Hail, Saudi Arabia.
Shahid Ud Din WaniDepartment of Pharmaceutics, CT Institute of Pharmaceutical Sciences, Jalandhar, India.
Riyaz Ali OsmaniDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India.
Amr S Abu LilaDepartment of Pharmaceutics, College of Pharmacy, University of Hail, Hail, Saudi Arabia.
El-Sayed KhafagyDepartment of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-kharj, Saudi Arabia.
Hany H ArabDepartment of Pharmacology and Toxicology, College of Pharmacy, Taif University, Taif, Saudi Arabia.
Hosahalli V GangadharappaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, India.
Ahmed N AllamDepartment of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Alexandria University · EGIndian Institute of Technology Bombay · INJSS Academy of Higher Education and Research · INPrince Sattam Bin Abdulaziz University · SATaif University · SAUniversity of Ha'il · SAZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silk fibroin (SF) is a natural polymeric biomaterial that is widely adopted for the preparation of drug delivery systems. Herein, we aimed to fabricate and characterize SF nanoparticles loaded with the selective estrogen receptor modulator; tamoxifen citrate (TC-SF-NPs) and to assess their

Indexed as

Antineoplastic AgentsApoptosisBreast NeoplasmsChemistry, PharmaceuticalDrug CarriersDrug LiberationDrug StabilityFibroinsHumansMCF-7 CellsNanoparticlesParticle SizeSurface PropertiesTamoxifenAntineoplastic AgentsDrug CarriersFibroinsTamoxifenBreast cancerin vitro cytotoxicitynanoparticlessilk fibrointamoxifen citrate

Identifiers

PMID34328806
PMCPMC8330732
OpenAlexW3183164963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.