Evidence map›Paper›PMID 34328747›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2021

Acetaminophen Interactions with Phospholipid Vesicles Induced Changes in Morphology and Lipid Dynamics.

Judith U De Mel, Sudipta Gupta, Sydney Harmon, Laura Stingaciu, Eric W Roth, Miriam Siebenbuerger, Markus Bleuel, Gerald J Schneider

Open access · hybridAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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  4. 3 Biotech · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Judith U De MelDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0001-7546-1491
Sudipta GuptaDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0001-6642-3776
Sydney HarmonDepartment of Chemistry, Colorado School of Mines, Golden, Colorado 80401, United States.
Laura StingaciuNeutron Sciences Directorate, Oak Ridge National Laboratory (ORNL), P.O.B 2008, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States.ORCID 0000-0003-2696-5233
Eric W RothDepartment of Materials Science and Engineering and NUANCE Center, Northwestern University, 2220 Campus Drive, Evanston, Illinois 60208, United States.
Miriam SiebenbuergerCenter of Advanced Microstructures and Devices, Louisiana State University, 6980 Jefferson Highway, Baton Rouge, Louisiana 70806, United States.
Markus BleuelNIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-8562, United States.
Gerald J SchneiderDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0002-5577-9328
Louisiana State University · USColorado School of Mines · USNational Institute of Standards and Technology · USNorthwestern University · USOak Ridge National Laboratory · US

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
NIGMS NIH HHS P41 GM103393US Department of Energy DE-SC0012432
6 · The paper itself

Abstract

Acetaminophen (APAP) or paracetamol, despite its wide and common use for pain and fever symptoms, shows a variety of side effects, toxic effects, and overdose effects. The most common form of toxic effects of APAP is in the liver where phosphatidylcholine is the major component of the cell membrane with additional associated functionalities. Although this is the case, the effects of APAP on pure phospholipid membranes have been largely ignored. Here, we used 1,2-di-(octadecenoyl)-

Indexed as

AcetaminophenPhospholipidsLipid BilayersPhosphatidylcholinesScattering, Small AngleX-Ray DiffractionAcetaminophenLipid BilayersPhosphatidylcholinesPhospholipids

Identifiers

PMID34328747
PMCPMC8359007
OpenAlexW3170334845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.