Evidence map›Paper›PMID 34328722›Full record

ArticleACS chemical biology2021

Methylotroph Quorum Sensing Signal Identification by Inverse Stable Isotopic Labeling.

Dale A Cummings, Alice I Snelling, Aaron W Puri

Abstract read
In one paragraph

Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Animal FAS-like polyketide synthases produce diverse polypropionates.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. AmBio · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dale A CummingsDepartment of Chemistry and the Henry Eyring Center for Cell and Genome Science, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0002-3996-7230
Alice I SnellingDepartment of Chemistry and the Henry Eyring Center for Cell and Genome Science, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0002-1867-1174
Aaron W PuriDepartment of Chemistry and the Henry Eyring Center for Cell and Genome Science, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0002-6378-678X

Funding

Methane-oxidizing bacterial communities: A novel source of bioactive chemical diversityR00GM118762 · NIGMS · UNIVERSITY OF UTAH · PI PURI, AARON WEBSTER · 2019 to 2021
$743k
NIGMS NIH HHS R00 GM118762
6 · The paper itself

Abstract

Natural products are an essential source of bioactive compounds. Isotopic labeling is an effective way to identify natural products that incorporate a specific precursor; however, this approach is limited by the availability of isotopically enriched precursors. We used an inverse stable isotopic labeling approach to identify natural products by growing bacteria on a

Indexed as

Acyl-ButyrolactonesCarbonCarbon IsotopesIsotope LabelingMethylobacteriaceaeMethylococcaceaeProof of Concept StudyQuorum SensingAcyl-ButyrolactonesCarbonCarbon-13Carbon Isotopes

Identifiers

PMID34328722
PMCPMC8496459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.