Evidence map›Paper›PMID 34328536›Full record

ArticleEuropean radiology2022

Inter-modality assessment of medial temporal lobe atrophy in a non-demented population: application of a visual rating scale template across radiologists with varying clinical experience.

Claes Håkansson, Ashkan Tamaddon, Henrik Andersson, Gustav Torisson, Gustav Mårtensson, My Truong, Mårten Annertz, Elisabet Londos, Isabella M Björkman-Burtscher, Oskar Hansson and 1 more

Abstract read
In one paragraph

Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claes HåkanssonDepartment of Imaging and Function, Skåne University Hospital, Lund, Sweden. claes.hakansson@med.lu.se.ORCID http://orcid.org/0000-0002-6032-2445
Ashkan TamaddonDepartment of Imaging and Function, Skåne University Hospital, Lund, Sweden.
Henrik AnderssonDepartment of Imaging and Function, Skåne University Hospital, Lund, Sweden.
Gustav TorissonDepartment of Translational Medicine, Clinical Infection Medicine, Lund University, Malmö, Sweden.
Gustav MårtenssonDepartment of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
My TruongDepartment of Imaging and Function, Skåne University Hospital, Lund, Sweden.
Mårten AnnertzDepartment of Imaging and Function, Skåne University Hospital, Lund, Sweden.
Elisabet LondosDepartment of Clinical Sciences Malmö, Clinical Memory Research Unit, Lund University, Malmö, Sweden.
Isabella M Björkman-BurtscherDepartment of Radiology, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Oskar HanssonDepartment of Clinical Sciences Malmö, Clinical Memory Research Unit, Lund University, Malmö, Sweden.
Danielle van WestenDepartment of Imaging and Function, Skåne University Hospital, Lund, Sweden.

Funding

Alzheimerfonden AF-939932Hjärnfonden FO2019-0326Knut och Alice Wallenbergs Stiftelse 2017-0383Marianne and Marcus Wallenberg Foundation 2015.0125Parkinsonfonden 1280/20Regionalt forskningsstöd 2020-0314Skånes universitetssjukhus 2020-O000028Swedish government under the ALF agreement 2018-Projekt0279Vetenskapsrådet 2016-00906
6 · The paper itself

Abstract

objectivesTo assess inter-modality agreement and accuracy for medial temporal lobe atrophy (MTA) ratings across radiologists with varying clinical experience in a non-demented population.

methodsFour raters (two junior radiologists and two senior neuroradiologists) rated MTA on CT and MRI scans using Scheltens' MTA scale. Ratings were compared to a consensus rating by two experienced neuroradiologists for estimation of true positive and negative rates (TPR and TNR) and over- and underestimation of MTA. Inter-modality agreement expressed as Cohen's κ (dichotomized data), Cohen's κ

resultsForty-nine subjects (median age 72 years, 27% abnormal MTA) with cognitive impairment were included. Only junior radiologists achieved adequate agreement expressed as Cohen's κ. All raters achieved adequate agreement expressed as Cohen's κ

conclusionWe conclude that radiologists with varying experience achieve adequate inter-modality agreement and similar accuracy when Scheltens' MTA scale is used to rate MTA on a non-demented population. However, TPR varied between radiologists which could be attributed to rating style differences. KEY POINTS: • Radiologists with varying experience achieve adequate inter-modality agreement with similar accuracy when Scheltens' MTA scale is used to rate MTA on a non-demented population. • Differences in rating styles might affect accuracy, this was most evident for senior neuroradiologists, and only junior radiologists achieved adequate agreement on dichotomized (abnormal/normal) ratings. • The use of an MTA scale template might compensate for varying clinical experience which could make it applicable for clinical use.

Indexed as

Alzheimer DiseaseCognitive DysfunctionAgedAtrophyHumansMagnetic Resonance ImagingRadiologistsTemporal LobeCognitive dysfunctionConsensusMagnetic resonance imagingRadiologistsTomography, X-ray computed

Identifiers

PMID34328536
PMCPMC8794965

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